Epithelial Systems Biology Laboratory

"Total Counts for Epithelial Cell Types in Rat and Mouse Kidney"


For step-by-step calculations download the speadsheet: Rat and Mouse Cell Counts.



Kidney Cell Counts

Segment /Cell type Total Cells per Kidney (milllions) Percent of Total Cells Total Protein Mass (mg) Percent of Total Protein Mass
Rat Mouse Rat Mouse Rat Mouse Rat Mouse
S1 Proximal 48.36 10.19 23.52 20.08 33031 8189 31.23 29.80
S2 Proximal 48.36 10.19 23.52 20.08 33031 8189 31.23 29.80
S3 Proximal 10.75 2.26 5.23 4.46 7340 1820 6.94 6.62
tDL - type 1 4.05 1.17 1.97 2.30 1497 432 1.42 1.57
tDL - type 2 3.31 0.44 1.61 0.86 815 108 0.77 0.39
tDL - type 3 1.81 0.73 0.88 1.43 537 215 0.51 0.78
tAL 3.00 0.87 1.46 1.72 741 215 0.70 0.78
MTAL 17.73 7.55 8.62 14.87 7125 3033 6.74 11.04
CTAL 17.77 3.61 8.64 7.12 5103 1038 4.82 3.78
DCT 19.90 3.78 9.68 7.45 8459 1607 8.00 5.85
CNT Cell 6.99 2.66 3.40 5.24 2011 764 1.90 2.78
CNT A-IC 1.17 0.44 0.57 0.87 335 127 0.32 0.46
CNT B-IC 3.50 1.33 1.70 2.62 1005 382 0.95 1.39
CCD PC 4.15 1.31 2.02 2.57 881 277 0.83 1.01
CCD B-IC 1.58 0.50 0.77 0.98 334 105 0.32 0.38
CCD A-IC 1.43 0.45 0.70 0.89 304 96 0.29 0.35
OMCD - PC 3.99 1.21 1.94 2.39 1013 308 0.96 1.12
OMCD - A-IC 2.50 0.76 1.22 1.50 635 193 0.60 0.70
OMCD - B-IC 0.16 0.05 0.08 0.10 41 12 0.04 0.04
IMCD 5.15 1.25 2.50 2.46 1544 374 1.46 1.36
SUM 205.63 50.74 105782.02 27484.00

Please cite: Clark JZ, Chen L, Chou CL, Jung HJ, Lee JW, Knepper MA. Representation and relative abundance of cell-type selective markers in whole-kidney RNA-Seq data. Kidney Int. 2019;95:787-796. PMID: 30826016.


(For podocyte counts from other labs see the: Rat and Mouse Cell Count Spreadsheet).




For questions or comments please contact us knepperm@nhlbi.nih.gov.