For step-by-step calculations download the speadsheet: Rat and Mouse Cell Counts.
| Segment /Cell type | Total Cells per Kidney (milllions) | Percent of Total Cells | Total Protein Mass (mg) | Percent of Total Protein Mass | ||||
| Rat | Mouse | Rat | Mouse | Rat | Mouse | Rat | Mouse | |
| S1 Proximal | 48.36 | 10.19 | 23.52 | 20.08 | 33031 | 8189 | 31.23 | 29.80 |
| S2 Proximal | 48.36 | 10.19 | 23.52 | 20.08 | 33031 | 8189 | 31.23 | 29.80 |
| S3 Proximal | 10.75 | 2.26 | 5.23 | 4.46 | 7340 | 1820 | 6.94 | 6.62 |
| tDL - type 1 | 4.05 | 1.17 | 1.97 | 2.30 | 1497 | 432 | 1.42 | 1.57 |
| tDL - type 2 | 3.31 | 0.44 | 1.61 | 0.86 | 815 | 108 | 0.77 | 0.39 |
| tDL - type 3 | 1.81 | 0.73 | 0.88 | 1.43 | 537 | 215 | 0.51 | 0.78 |
| tAL | 3.00 | 0.87 | 1.46 | 1.72 | 741 | 215 | 0.70 | 0.78 |
| MTAL | 17.73 | 7.55 | 8.62 | 14.87 | 7125 | 3033 | 6.74 | 11.04 |
| CTAL | 17.77 | 3.61 | 8.64 | 7.12 | 5103 | 1038 | 4.82 | 3.78 |
| DCT | 19.90 | 3.78 | 9.68 | 7.45 | 8459 | 1607 | 8.00 | 5.85 |
| CNT Cell | 6.99 | 2.66 | 3.40 | 5.24 | 2011 | 764 | 1.90 | 2.78 |
| CNT A-IC | 1.17 | 0.44 | 0.57 | 0.87 | 335 | 127 | 0.32 | 0.46 |
| CNT B-IC | 3.50 | 1.33 | 1.70 | 2.62 | 1005 | 382 | 0.95 | 1.39 |
| CCD PC | 4.15 | 1.31 | 2.02 | 2.57 | 881 | 277 | 0.83 | 1.01 |
| CCD B-IC | 1.58 | 0.50 | 0.77 | 0.98 | 334 | 105 | 0.32 | 0.38 |
| CCD A-IC | 1.43 | 0.45 | 0.70 | 0.89 | 304 | 96 | 0.29 | 0.35 |
| OMCD - PC | 3.99 | 1.21 | 1.94 | 2.39 | 1013 | 308 | 0.96 | 1.12 |
| OMCD - A-IC | 2.50 | 0.76 | 1.22 | 1.50 | 635 | 193 | 0.60 | 0.70 |
| OMCD - B-IC | 0.16 | 0.05 | 0.08 | 0.10 | 41 | 12 | 0.04 | 0.04 |
| IMCD | 5.15 | 1.25 | 2.50 | 2.46 | 1544 | 374 | 1.46 | 1.36 |
| SUM | 205.63 | 50.74 | 105782.02 | 27484.00 | ||||
Please cite: Clark JZ, Chen L, Chou CL, Jung HJ, Lee JW, Knepper MA. Representation and relative abundance of cell-type selective markers in whole-kidney RNA-Seq data. Kidney Int. 2019;95:787-796. PMID: 30826016.
(For podocyte counts from other labs see the: Rat and Mouse Cell Count Spreadsheet).
For questions or comments please contact us knepperm@nhlbi.nih.gov.