National Heart, Lung, and Blood Institute

Epithelial Systems Biology Laboratory (ESBL)


V2 Receptor-specific Vasopressin Signaling in mpkCCD Cells

Vasopressin Signaling Network: Undirected graph depicting the mapping of proteins containing altered phosphorylation sites to specific cellular functions or structures [blue nodes]. The green and red nodes indicate specific phosphorylation sites altered in response to 0.1 nM dDAVP administration (green, increased, red, decreased). Network was constructed initially in STRING and manually extended to the full data set using Gene Ontology terms and Pubmed entries. Cytoscape was used for visualization.

Database was created by Karim Salhadar, Arnab Datta, and Mark Knepper in the Epithelial Systems Biology Laboratory (Mark Knepper, Chief) at the National Heart, Lung and Blood Institute as part of its Kidney Systems Biology Project.

For questions and concerns please contact: knepperm@nhlbi.nih.gov.

Click here to download PDF version of Vasopressin Signaling Network.

Press Ctrl and + to zoom in. Press Ctrl and - to zoom out. Press Ctrl and 0 to restore the original size.

Phosphoproteomic Network