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National Heart, Lung, and Blood Institute

Epithelial Systems Biology Laboratory (ESBL)


Knepper Laboratory

Renal Inner Medulla Free-Energy Calculator

The Renal Inner Medulla Free-Energy Calculator is a tool that allows the user to calculate steady-state mass balance and free-energy balance requirements for the renal inner medulla given a particular set of flows and concentrations in loops of Henle, collecting ducts, and vasa recta at the border between the inner and outer medulla of the mammalian kidney.  The free-energy calculations implement the equations of Stephenson, Tewarson, and Mejia.  Sample data may be found by clicking here.

Frequently Asked Questions

To download the Java executable [.jar] file, click here.

This program was created by Ryan Vilbig, Trairak Pisitkun, Joe Zischkau, Abhijit Sarkar, and Mark Knepper.  Contact us with questions or comments.

Go to ESBL Main Page

Renal Inner Medulla Free-Energy Calculator is hosted and supported by: Biowulf at the NIH


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