National Heart, Lung, and Blood Institute

Epithelial Systems Biology Laboratory (ESBL)


Knepper Laboratory

Renal Inner Medulla Free-Energy Calculator

The Renal Inner Medulla Free-Energy Calculator is a tool that allows the user to calculate steady-state mass balance and free-energy balance requirements for the renal inner medulla given a particular set of flows and concentrations in loops of Henle, collecting ducts, and vasa recta at the border between the inner and outer medulla of the mammalian kidney.  The free-energy calculations implement the equations of Stephenson, Tewarson, and Mejia.  Sample data may be found by clicking here.

Frequently Asked Questions

To download the Java executable [.jar] file, click here.

This program was created by Ryan Vilbig, Trairak Pisitkun, Joe Zischkau, Abhijit Sarkar, and Mark Knepper. Contact us with questions or comments: knep@helix.nih.gov

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