National Heart, Lung, and Blood Institute

Epithelial Systems Biology Laboratory (ESBL)


Aldosterone Target Genes in Collecting Duct

This database is a compendium of mineralocortocoid receptor (Nr3c2) target genes from multiple publications. References are given as PMID numbers.

Database was created by Angela Mak and Mark Knepper in the Epithelial Systems Biology Laboratory (Mark Knepper, Chief) at the National Heart, Lung and Blood Institute as part of its Kidney Systems Biology Project.

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Gene Symbol  Annotation Reference UniProt no.
Atf3 cyclic AMP-dependent transcription factor ATF-3 isoform X2 Fakitsas, 2007.  ( PMID: 17344426) Q60765.1
B2m beta-2-microglobulin Robert-Nicoud, 2001. (PMID: 11226305) P01887.2
Cox7a1 cytochrome c oxidase subunit 7A1, mitochondrial precursor Robert-Nicoud, 2001. (PMID: 11226305) P56392.1
Crem cAMP-responsive element modulator isoform 16 Fakitsas, 2007.  ( PMID: 17344426) P27699.2
Cstb cystatin-B Robert-Nicoud, 2001. (PMID: 11226305) Q62426.1
Edn1 endothelin-1 Wong, 2007.  (PMID: 17218419) P22387.3
Eif1 eukaryotic translation initiation factor 1 Robert-Nicoud, 2001. (PMID: 11226305) P48024.2
Fkbp5 peptidyl-prolyl cis-trans isomerase FKBP5 Fakitsas, 2007.  ( PMID: 17344426) Q64378.1
Fosl2 fos-related antigen 2 Spindler, 1999. (PMID: 10329965) P47930.2
Gadd45g growth arrest and DNA damage-inducible protein GADD45 gamma Fakitsas, 2007.  ( PMID: 17344426) Q9Z111.1
Grem2 gremlin-2 Fakitsas, 2007.  ( PMID: 17344426) O88273.1
H2-D1 H-2 class I histocompatibility antigen, D-B alpha chain precursor Robert-Nicoud, 2001. (PMID: 11226305) P01895.1
H2-L histocompatibility 2, D region locus L Robert-Nicoud, 2001. (PMID: 11226305) P01897.2
Kras GTPase KRas Spindler, 1999. (PMID: 10329965) P32883.1
Krt18 keratin, type I cytoskeletal 18 Robert-Nicoud, 2001. (PMID: 11226305) P05784.5
Krt8 keratin, type II cytoskeletal 8 Robert-Nicoud, 2001. (PMID: 11226305) P11679.4
Mpg DNA-3-methyladenine glycosylase Robert-Nicoud, 2001. (PMID: 11226305) Q04841.3
Nme2 nucleoside diphosphate kinase B Robert-Nicoud, 2001. (PMID: 11226305) Q01768.1
Oas1a 2'-5'-oligoadenylate synthase 1A Robert-Nicoud, 2001. (PMID: 11226305) P11928.2
Plac8 placenta-specific gene 8 protein Robert-Nicoud, 2001. (PMID: 11226305) Q9JI48.1
Rpl12 60S ribosomal protein L12 Robert-Nicoud, 2001. (PMID: 11226305) P35979.2
Rpl26 60S ribosomal protein L26 isoform X2 Robert-Nicoud, 2001. (PMID: 11226305) P61255.1
Rps29 40S ribosomal protein S29 Robert-Nicoud, 2001. (PMID: 11226305) P62274.2
Scnn1a amiloride-sensitive sodium channel subunit alpha Husted, 2007 (PMID: 17609289) Q61180.2
Serinc3 serine incorporator 3 Robert-Nicoud, 2001. (PMID: 11226305) Q9QZI9.2
Sgk1 serine/threonine-protein kinase Sgk1 isoform a Fakitsas, 2007 (PMID: 17344426), Náray-Fejes-Tóth, 2000 (PMID: 17344426) Q9WVC6.1
Tnfrsf12a tumor necrosis factor receptor superfamily member 12A isoform 2 precursor Robert-Nicoud, 2001. (PMID: 11226305) Q9CR75.1
Tsc22d3 TSC22 domain family protein 3 (GILZ) Robert-Nicoud, 2001. (PMID: 11226305) Q9Z2S7.2
Usp2 ubiquitin carboxyl-terminal hydrolase 2  Fakitsas, 2007.  ( PMID: 17344426) O88623.2
Ypel2 protein yippee-like 2 isoform X2 Fakitsas, 2007.  ( PMID: 17344426) Q65Z95.1

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Gene Symbol  Annotation Reference UniProt no.