Proteins that determine cytoplasmic free calcium levels in cells. Converted to mouse gene symbols. From: Mehta et al. "ADPKD-omics": determinants of cyclic AMP levels in renal epithelial cells. Kidney Int. 2022; 101: 47-62. PMID: 34757121.
Database was created by Angela Mak and Mark Knepper in the Epithelial Systems Biology Laboratory (Mark Knepper, Chief) at the National Heart, Lung and Blood Institute as part of its Kidney Systems Biology Project.
| Gene Symbol | Action | Annotation | Uniprot Number |
| Atp2a1 | endoplasmic reticulum Ca transport | sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | Q8R429 |
| Atp2a2 | endoplasmic reticulum Ca transport | sarcoplasmic/endoplasmic reticulum calcium ATPase 2 | O55143 |
| Atp2a3 | endoplasmic reticulum Ca transport | sarcoplasmic/endoplasmic reticulum calcium ATPase 3 | Q64518 |
| Atp2b1 | plasma membrane Ca ATPase | plasma membrane calcium-transporting ATPase 1 | G5E829 |
| Atp2b2 | plasma membrane Ca ATPase | plasma membrane calcium-transporting ATPase 2 | Q9R0K7 |
| Atp2b3 | plasma membrane Ca ATPase | plasma membrane calcium-transporting ATPase 3 | Q8C048 |
| Atp2b4 | plasma membrane Ca ATPase | plasma membrane calcium-transporting ATPase 4 | Q6Q477 |
| Atp2c1 | plasma membrane Ca ATPase | calcium-transporting ATPase type 2C member 1 | Q80XR2 |
| Itpr1 | endoplasmic reticulum Ca transport | inositol 1,4,5-trisphosphate receptor type 1 | P11881 |
| Itpr2 | endoplasmic reticulum Ca transport | inositol 1,4,5-trisphosphate receptor type 2 | Q9Z329 |
| Itpr3 | endoplasmic reticulum Ca transport | inositol 1,4,5-trisphosphate receptor type 3 | P70227 |
| Letm1 | mitochondrial Ca transport | mitochondrial proton/calcium exchanger protein | Q9Z2I0 |
| Mcoln1 | plasma membrane/endosomal Ca channel | mucolipin-1 | Q99J21 |
| Mcoln2 | plasma membrane/endosomal Ca channel | mucolipin-2 | Q8K595 |
| Mcoln3 | plasma membrane/endosomal Ca channel | mucolipin-3 | Q8R4F0 |
| Mcu | mitochondrial Ca transport | calcium uniporter protein, mitochondrial | Q3UMR5 |
| Mcub | mitochondrial Ca transport | calcium uniporter regulatory subunit MCUb, mitochondrial | Q810S1 |
| Micu1 | mitochondrial Ca transport | calcium uptake protein 1, mitochondrial | Q8VCX5 |
| Micu2 | mitochondrial Ca transport | calcium uptake protein 2, mitochondrial | Q8CD10 |
| Micu3 | mitochondrial Ca transport | calcium uptake protein 3, mitochondrial | Q9CTY5 |
| Orai1 | plasma membrane/endosomal Ca channel | calcium release-activated calcium channel protein 1 | Q8BWG9 |
| Orai2 | plasma membrane/endosomal Ca channel | protein orai-2 | Q8BH10 |
| Orai3 | plasma membrane/endosomal Ca channel | protein orai-3 | Q6P8G8 |
| Pkd2 | plasma membrane/endosomal Ca channel | polycystin-2 | O35245 |
| Pkd2l1 | plasma membrane/endosomal Ca channel | polycystic kidney disease 2-like 1 protein | A2A259 |
| Ryr1 | endoplasmic reticulum Ca transport | ryanodine receptor 1 | E9PZQ0 |
| Ryr2 | endoplasmic reticulum Ca transport | ryanodine receptor 2 | E9Q401 |
| Ryr3 | endoplasmic reticulum Ca transport | ryanodine receptor 3 | A2AGL3 |
| Slc24a1 | plasma membrane Ca exchange | sodium/potassium/calcium exchanger 1 | Q91WD8 |
| Slc24a2 | plasma membrane Ca exchange | sodium/potassium/calcium exchanger 2 | Q8BUN9 |
| Slc24a3 | plasma membrane Ca exchange | sodium/potassium/calcium exchanger 3 | Q99PD7 |
| Slc24a4 | plasma membrane Ca exchange | sodium/potassium/calcium exchanger 4 | Q8CGQ8 |
| Slc24a5 | plasma membrane Ca exchange | sodium/potassium/calcium exchanger 5 | Q8C261 |
| Slc8a1 | plasma membrane Ca exchange | sodium/calcium exchanger 1 | P70414 |
| Slc8a2 | plasma membrane Ca exchange | sodium/calcium exchanger 2 | Q8K596 |
| Slc8a3 | plasma membrane Ca exchange | sodium/calcium exchanger 3 | S4R2P9 |
| Slc8b1 | mitochondrial Ca transport | mitochondrial sodium/calcium exchanger protein | Q925Q3 |
| Smdt1 | mitochondrial Ca transport | essential MCU regulator, mitochondrial | Q9DB10 |
| Trpc1 | plasma membrane/endosomal Ca channel | short transient receptor potential channel 1 | Q61056 |
| Trpc2 | plasma membrane/endosomal Ca channel | short transient receptor potential channel 2 | Q9R244 |
| Trpc3 | plasma membrane/endosomal Ca channel | short transient receptor potential channel 3 | Q9QZC1 |
| Trpc4 | plasma membrane/endosomal Ca channel | short transient receptor potential channel 4 | Q9QUQ5 |
| Trpc5 | plasma membrane/endosomal Ca channel | short transient receptor potential channel 5 | Q9QX29 |
| Trpc6 | plasma membrane/endosomal Ca channel | short transient receptor potential channel 6 | Q61143 |
| Trpc7 | plasma membrane/endosomal Ca channel | short transient receptor potential channel 7 | Q9WVC5 |
| Trpv1 | plasma membrane/endosomal Ca channel | transient receptor potential cation channel subfamily V member 1 | Q704Y3 |
| Trpv2 | plasma membrane/endosomal Ca channel | transient receptor potential cation channel subfamily V member 2 | Q9WTR1 |
| Trpv3 | plasma membrane/endosomal Ca channel | transient receptor potential cation channel subfamily V member 3 | Q8K424 |
| Trpv4 | plasma membrane/endosomal Ca channel | transient receptor potential cation channel subfamily V member 4 | Q9EPK8 |
| Trpv5 | plasma membrane/endosomal Ca channel | transient receptor potential cation channel subfamily V member 5 | P69744 |
| Trpv6 | plasma membrane/endosomal Ca channel | transient receptor potential cation channel subfamily V member 6 | Q91WD2 |
| Gene Symbol | Action | Annotation | Uniprot Number |
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