The gene list on this page consists of all genes in the KEGG "Cell cycle - Homo sapiens (human)" pathway.
Database was created by Angela Mak and Mark Knepper in the Epithelial Systems Biology Laboratory (Mark Knepper, Chief) at the National Heart, Lung and Blood Institute as part of its Kidney Systems Biology Project.
Gene symbol | Annotation | UniProt No. |
ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | P00519.4 |
ANAPC1 | anaphase promoting complex subunit 1 | Q9H1A4.1 |
ANAPC10 | anaphase promoting complex subunit 10 | Q9UM13.1 |
ANAPC11 | anaphase promoting complex subunit 11 | Q9NYG5.1 |
ANAPC13 | anaphase promoting complex subunit 13 | Q9BS18.1 |
ANAPC2 | anaphase promoting complex subunit 2 | Q9UJX6.1 |
ANAPC4 | anaphase promoting complex subunit 4 | Q9UJX5.2 |
ANAPC5 | anaphase promoting complex subunit 5 | Q9UJX4.2 |
ANAPC7 | anaphase promoting complex subunit 7 | Q9UJX3.5 |
ATM | ATM serine/threonine kinase | Q13315.4 |
ATR | ATR serine/threonine kinase | Q13535.3 |
BUB1 | BUB1 mitotic checkpoint serine/threonine kinase | O43683.1 |
BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B | O60566.3 |
BUB3 | BUB3, mitotic checkpoint protein | O43684.1 |
CCNA1 | cyclin A1 | P78396.1 |
CCNA2 | cyclin A2 | P20248.2 |
CCNB1 | cyclin B1 | P14635.1 |
CCNB2 | cyclin B2 | O95067.1 |
CCNB3 | cyclin B3 | Q8WWL7.2 |
CCND1 | cyclin D1 | P24385.1 |
CCND2 | cyclin D2 | P30279.1 |
CCND3 | cyclin D3 | P30281.2 |
CCNE1 | cyclin E1 | P24864.2 |
CCNE2 | cyclin E2 | O96020.1 |
CCNH | cyclin H | P51946.1 |
CDC14A | cell division cycle 14A | Q9UNH5.1 |
CDC14B | cell division cycle 14B | O60729.1 |
CDC16 | cell division cycle 16 | Q13042.2 |
CDC20 | cell division cycle 20 | Q12834.2 |
CDC23 | cell division cycle 23 | Q9UJX2.3 |
CDC25A | cell division cycle 25A | P30304.2 |
CDC25B | cell division cycle 25B | P30305.2 |
CDC25C | cell division cycle 25C | P30307.2 |
CDC26 | cell division cycle 26 | Q8NHZ8.1 |
CDC27 | cell division cycle 27 | P30260.2 |
CDC45 | cell division cycle 45 | O75419.1 |
CDC6 | cell division cycle 6 | Q99741.1 |
CDC7 | cell division cycle 7 | O00311.1 |
CDK1 | cyclin dependent kinase 1 | P06493.3 |
CDK2 | cyclin dependent kinase 2 | P24941.2 |
CDK4 | cyclin dependent kinase 4 | P11802.2 |
CDK6 | cyclin dependent kinase 6 | Q00534.1 |
CDK7 | cyclin dependent kinase 7 | P50613.1 |
CDKN1A | cyclin dependent kinase inhibitor 1A | P38936.3 |
CDKN1B | cyclin dependent kinase inhibitor 1B | P46527.1 |
CDKN1C | cyclin dependent kinase inhibitor 1C | P49918.1 |
CDKN2A | cyclin dependent kinase inhibitor 2A | Q8N726.2 |
CDKN2B | cyclin dependent kinase inhibitor 2B | P42772.1 |
CDKN2C | cyclin dependent kinase inhibitor 2C | P42773.1 |
CDKN2D | cyclin dependent kinase inhibitor 2D | P55273.1 |
CHEK1 | checkpoint kinase 1 | O14757.2 |
CHEK2 | checkpoint kinase 2 | O96017.1 |
CREBBP | CREB binding protein | Q92793.3 |
CUL1 | cullin 1 | Q13616.2 |
DBF4 | DBF4 zinc finger | Q9UBU7.1 |
E2F1 | E2F transcription factor 1 | Q01094.1 |
E2F2 | E2F transcription factor 2 | Q14209.1 |
E2F3 | E2F transcription factor 3 | O00716.1 |
E2F4 | E2F transcription factor 4 | Q16254.2 |
E2F5 | E2F transcription factor 5 | Q15329.1 |
EP300 | E1A binding protein p300 | Q09472.2 |
ESPL1 | extra spindle pole bodies like 1, separase | Q14674.3 |
FZR1 | fizzy and cell division cycle 20 related 1 | Q9UM11.2 |
GADD45A | growth arrest and DNA damage inducible alpha | P24522.1 |
GADD45B | growth arrest and DNA damage inducible beta | O75293.1 |
GADD45G | growth arrest and DNA damage inducible gamma | O95257.1 |
GSK3B | glycogen synthase kinase 3 beta | P49841.2 |
HDAC1 | histone deacetylase 1 | Q13547.1 |
HDAC2 | histone deacetylase 2 | Q92769.2 |
MAD1L1 | MAD1 mitotic arrest deficient like 1 | Q9Y6D9.2 |
MAD2L1 | mitotic arrest deficient 2 like 1 | Q13257.1 |
MAD2L2 | mitotic arrest deficient 2 like 2 | Q9UI95.2 |
MCM2 | minichromosome maintenance complex component 2 | P49736.4 |
MCM3 | minichromosome maintenance complex component 3 | P25205.3 |
MCM4 | minichromosome maintenance complex component 4 | P33991.5 |
MCM5 | minichromosome maintenance complex component 5 | P33992.5 |
MCM6 | minichromosome maintenance complex component 6 | Q14566.1 |
MCM7 | minichromosome maintenance complex component 7 | P33993.4 |
MDM2 | MDM2 proto-oncogene | Q00987.1 |
MYC | MYC proto-oncogene, bHLH transcription factor | P01106.1 |
ORC1 | origin recognition complex subunit 1 | Q13415.2 |
ORC2 | origin recognition complex subunit 2 | Q13416.2 |
ORC3 | origin recognition complex subunit 3 | Q9UBD5.1 |
ORC4 | origin recognition complex subunit 4 | O43929.2 |
ORC5 | origin recognition complex subunit 5 | O43913.1 |
ORC6 | origin recognition complex subunit 6 | Q9Y5N6.1 |
PCNA | proliferating cell nuclear antigen | P12004.1 |
PKMYT1 | protein kinase, membrane associated tyrosine/threonine 1 | Q99640.1 |
PLK1 | polo like kinase 1 | P53350.1 |
PRKDC | protein kinase, DNA-activated, catalytic polypeptide | P78527.3 |
PTTG1 | pituitary tumor-transforming 1 | O95997.1 |
PTTG2 | pituitary tumor-transforming 2 | Q9NZH5.2 |
RAD21 | RAD21 cohesin complex component | O60216.2 |
RB1 | RB transcriptional corepressor 1 | P06400.2 |
RBL1 | RB transcriptional corepressor like 1 | P28749.3 |
RBL2 | RB transcriptional corepressor like 2 | Q08999.3 |
RBX1 | ring-box 1 | P62877.1 |
SFN | stratifin | P31947.1 |
SKP1 | S-phase kinase associated protein 1 | P63208.2 |
SKP2 | S-phase kinase associated protein 2 | Q13309.2 |
SMAD2 | SMAD family member 2 | Q15796.1 |
SMAD3 | SMAD family member 3 | P84022.1 |
SMAD4 | SMAD family member 4 | Q13485.1 |
SMC1A | structural maintenance of chromosomes 1A | Q14683.2 |
SMC1B | structural maintenance of chromosomes 1B | Q8NDV3.2 |
SMC3 | structural maintenance of chromosomes 3 | Q9UQE7.2 |
STAG1 | stromal antigen 1 | Q8WVM7.3 |
STAG2 | stromal antigen 2 | Q8N3U4.3 |
TFDP1 | transcription factor Dp-1 | Q14186.1 |
TFDP2 | transcription factor Dp-2 | Q14188.2 |
TGFB1 | transforming growth factor beta 1 | P01137.2 |
TGFB2 | transforming growth factor beta 2 | P61812.1 |
TGFB3 | transforming growth factor beta 3 | P10600.1 |
TP53 | tumor protein p53 | P04637.4 |
TTK | TTK protein kinase | P33981.2 |
WEE1 | WEE1 G2 checkpoint kinase | P30291.2 |
WEE2 | WEE1 homolog 2 | P0C1S8.2 |
YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta | P31946.3 |
YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon | P62258.1 |
YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma | P61981.2 |
YWHAH | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta | Q04917.4 |
YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta | P27348.1 |
YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta | P63104.1 |
ZBTB17 | zinc finger and BTB domain containing 17 | Q13105.3 |
Gene symbol | Annotation | UniProt No. |