Curated from KEGG "Glucagon Signaling Pathway" at https://www.genome.jp/pathway/hsa04922
Database was created by Angela Mak and Mark Knepper in the Epithelial Systems Biology Laboratory (Mark Knepper, Chief) at the National Heart, Lung and Blood Institute as part of its Kidney Systems Biology Project.
| Gene Symbol | Protein Name | UniProt Number |
| Acaca | acetyl-CoA carboxylase 1 | Q5SWU9 |
| Acacb | acetyl-CoA carboxylase 2 isoform 2 precursor | E9Q4Z2 |
| Adcy2 | adenylate cyclase type 2 | Q80TL1 |
| Akt1 | RAC-alpha serine/threonine-protein kinase isoform 1 | P31750 |
| Akt2 | RAC-beta serine/threonine-protein kinase | Q60823 |
| Akt3 | RAC-gamma serine/threonine-protein kinase | Q9WUA6 |
| Atf2 | cyclic AMP-dependent transcription factor ATF-2 isoform 3 | P16951 |
| Atf4 | cyclic AMP-dependent transcription factor ATF-4 | Q06507 |
| Calm1 | calmodulin-1 isoform 1 | P0DP26 |
| Calm2 | calmodulin-2 isoform 2 | P0DP27 |
| Calm3 | calmodulin-3 | P0DP28 |
| Calml3 | calmodulin-like protein 3 | Q9D6P8 |
| Calml4 | calmodulin-like protein 4 isoform b | Q91WQ9 |
| Calml5 | calmodulin-like protein 5 | Q9NZT1 |
| Calml6 | calmodulin-like protein | Q8TD86 |
| Camk2a | calcium/calmodulin-dependent protein kinase type II subunit alpha isoform 2 | P11798 |
| Camk2b | calcium/calmodulin-dependent protein kinase type II subunit beta isoform 3 | P28652 |
| Camk2d | calcium/calmodulin-dependent protein kinase type II subunit delta isoform 9 | Q6PHZ2 |
| Camk2g | calcium/calmodulin-dependent protein kinase type II subunit gamma isoform 4 | Q923T9 |
| Cpt1a | carnitine O-palmitoyltransferase 1, liver isoform | P97742 |
| Cpt1b | carnitine O-palmitoyltransferase 1, muscle isoform | Q924X2 |
| Cpt1c | carnitine O-palmitoyltransferase 1, brain isoform isoform 2 | Q8BGD5 |
| Creb1 | cyclic AMP-responsive element-binding protein 1 isoform C | Q01147 |
| Creb3 | cyclic AMP-responsive element-binding protein 3 | Q61817 |
| Creb3l1 | cyclic AMP-responsive element-binding protein 3-like protein 1 | Q9Z125 |
| Creb3l2 | cyclic AMP-responsive element-binding protein 3-like protein 2 | Q8BH52 |
| Creb3l3 | cyclic AMP-responsive element-binding protein 3-like protein 3 | Q91XE9 |
| Creb3l4 | cyclic AMP-responsive element-binding protein 3-like protein 4 isoform 2 | Q9D2A5 |
| Creb5 | cyclic AMP-responsive element-binding protein 5 isoform 1 | Q8K1L0 |
| Crebbp | histone lysine acetyltransferase CREBBP | P45481 |
| Crtc2 | CREB-regulated transcription coactivator 2 isoform 2 | Q3U182 |
| Ep300 | histone acetyltransferase p300 | B2RWS6 |
| Fbp1 | fructose-1,6-bisphosphatase 1 | Q9QXD6 |
| Foxo1 | forkhead box protein O1 | Q9R1E0 |
| G6pc | glucose-6-phosphatase catalytic subunit 1 | P35576 |
| G6pc2 | glucose-6-phosphatase 2 isoform 3 | Q9Z186 |
| G6pc3 | glucose-6-phosphatase 3 | Q6NSQ9 |
| Gck | hexokinase-4 isoform 1 | P52792 |
| Gnaq | guanine nucleotide-binding protein G(q) subunit alpha | P21279 |
| Gnas | protein ALEX isoform i | Q9Z0F1 |
| Gys1 | glycogen [starch] synthase, muscle | Q9Z1E4 |
| Gys2 | glycogen [starch] synthase, liver | Q8VCB3 |
| Itpr1 | inositol 1,4,5-trisphosphate receptor type 1 | P11881 |
| Itpr2 | inositol 1,4,5-trisphosphate receptor type 2 isoform 1 | Q9Z329 |
| Itpr3 | inositol 1,4,5-trisphosphate receptor type 3 | P70227 |
| Ldha | L-lactate dehydrogenase A chain isoform 2 | P06151 |
| Ldhal6a | L-lactate dehydrogenase A-like 6A | Q6ZMR3 |
| Ldhal6b | L-lactate dehydrogenase A-like 6B | Q9BYZ2 |
| Ldhb | L-lactate dehydrogenase B chain isoform Ldhbx | P16125 |
| Ldhc | L-lactate dehydrogenase C chain | P00342 |
| Pck1 | phosphoenolpyruvate carboxykinase, cytosolic [GTP] | Q9Z2V4 |
| Pck2 | phosphoenolpyruvate carboxykinase [GTP], mitochondrial | Q8BH04 |
| Pde3b | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | Q61409 |
| Pdha1 | pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial precursor | P35486 |
| Pdha2 | pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial precursor | P35487 |
| Pdhb | pyruvate dehydrogenase E1 component subunit beta, mitochondrial precursor | Q9D051 |
| Pfkfb1 | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 isoform 1 | P70266 |
| Pfkl | ATP-dependent 6-phosphofructokinase, liver type isoform 2 | P12382 |
| Pgam1 | phosphoglycerate mutase 1 | Q9DBJ1 |
| Pgam2 | phosphoglycerate mutase 2 | O70250 |
| Pgam4 | probable phosphoglycerate mutase 4 | Q8N0Y7 |
| Phka1 | phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform isoform 1 | P18826 |
| Phka2 | phosphorylase b kinase regulatory subunit alpha, liver isoform isoform a | Q8BWJ3 |
| Phkb | phosphorylase b kinase regulatory subunit beta isoform 1 | Q7TSH2 |
| Phkg1 | phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform | P07934 |
| Phkg2 | phosphorylase b kinase gamma catalytic chain, liver/testis isoform isoform 2 | Q9DB30 |
| Pkm | pyruvate kinase PKM isoform M1 | P52480 |
| Plcb1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 isoform 1 | Q9Z1B3 |
| Plcb2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 isoform b | A3KGF7 |
| Plcb3 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 isoform b | P51432 |
| Plcb4 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform c | Q9Z2T3 |
| Ppara | peroxisome proliferator-activated receptor alpha | P23204 |
| Ppargc1a | peroxisome proliferator-activated receptor gamma coactivator 1-alpha isoform c | O70343 |
| Ppp3ca | protein phosphatase 3 catalytic subunit alpha isoform 2 | P63328 |
| Ppp3cb | serine/threonine-protein phosphatase 2B catalytic subunit beta isoform isoform 1 | P48453 |
| Ppp3cc | serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform isoform 4 | P48455 |
| Ppp3r1 | calcineurin subunit B type 1 | Q63810 |
| Ppp3r2 | calcineurin subunit B type 2 | Q63811 |
| Ppp4c | serine/threonine-protein phosphatase 4 catalytic subunit | P97470 |
| Ppp4r3a | serine/threonine-protein phosphatase 4 regulatory subunit 3A isoform 2 | Q6P2K6 |
| Ppp4r3b | serine/threonine-protein phosphatase 4 regulatory subunit 3B isoform 3 | Q922R5 |
| Prkaa1 | 5'-AMP-activated protein kinase catalytic subunit alpha-1 isoform 2 | Q5EG47 |
| Prkaa2 | 5'-AMP-activated protein kinase catalytic subunit alpha-2 isoform 2 | Q8BRK8 |
| Prkab1 | 5'-AMP-activated protein kinase subunit beta-1 | Q9R078 |
| Prkab2 | 5'-AMP-activated protein kinase subunit beta-2 | Q6PAM0 |
| Prkaca | cAMP-dependent protein kinase catalytic subunit alpha isoform 2 | P05132 |
| Prkacb | cAMP-dependent protein kinase catalytic subunit beta isoform 3 | P68181 |
| Prkacb | cAMP-dependent protein kinase catalytic subunit gamma | P22612 |
| Prkag1 | 5'-AMP-activated protein kinase subunit gamma-1 | O54950 |
| Prkag2 | 5'-AMP-activated protein kinase subunit gamma-2 isoform 1 | Q91WG5 |
| Prkag3 | 5'-AMP-activated protein kinase subunit gamma-3 | Q8BGM7 |
| Prmt1 | protein arginine N-methyltransferase 1 isoform 3 | Q9JIF0 |
| Pygb | glycogen phosphorylase, brain form | Q8CI94 |
| Pygl | glycogen phosphorylase, liver form | Q9ET01 |
| Pygm | glycogen phosphorylase, muscle form | Q9WUB3 |
| Sik1 | serine/threonine-protein kinase SIK1 | Q60670 |
| Sik1 | serine/threonine-protein kinase SIK1 | Q60670 |
| Sik2 | serine/threonine-protein kinase SIK2 isoform 3 | Q8CFH6 |
| Sirt1 | NAD-dependent protein deacetylase sirtuin-1 isoform 2 | Q923E4 |
| Slc2a1 | solute carrier family 2, facilitated glucose transporter member 1 | P17809 |
| Slc2a2 | solute carrier family 2, facilitated glucose transporter member 2 | P14246 |
| Gene Symbol | Protein Name | UniProt Number |
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