This database lists consensus NF-κB target genes from two curated lists at https://www.bu.edu/nf-kb/gene-resources/target-genes/ and http://bioinfo.lifl.fr/NF-KB/.
Database was created by Angela Mak and Mark Knepper in the Epithelial Systems Biology Laboratory (Mark Knepper, Chief) at the National Heart, Lung and Blood Institute as part of its Kidney Systems Biology Project.
Gene Symbol | Annotation | UniProt Mouse |
Ager | advanced glycosylation end product-specific receptor | Q62151.2 |
Alox12b | arachidonate 12-lipoxygenase, 12R-type | O70582.1 |
Apoc3 | apolipoprotein C-III | P33622.2 |
B2m | beta-2-microglobulin | P01887.2 |
Bcl2 | apoptosis regulator Bcl-2 | P10417.3 |
Bcl2a1 | bcl-2-related protein A1 | Q07440.1 |
Bcl2l1 | bcl-2-like protein 1 | Q64373.1 |
Bcl3 | B-cell lymphoma 3 protein homolog | Q9Z2F6.2 |
Bdkrb1 | B1 bradykinin receptor | Q61125.1 |
Ccl11 | eotaxin | P48298.1 |
Ccl15 | C-C motif chemokine 15 preproprotein | Q16663.3 |
Ccl2 | C-C motif chemokine 2 | P10148.1 |
Ccl5 | C-C motif chemokine 5 | P30882.2 |
Ccnd1 | G1/S-specific cyclin-D1 | P25322.1 |
Ccr5 | C-C chemokine receptor type 5 | P51682.3 |
Ccr7 | C-C chemokine receptor type 7 | P47774.2 |
Cd209 | CD209 antigen isoform 8 | Q9NNX6.1 |
Cd3g | T-cell surface glycoprotein CD3 gamma chain | P11942.1 |
Cd40 | tumor necrosis factor receptor superfamily member 5 | P27512.3 |
Cd40lg | CD40 ligand | P27548.2 |
Cd44 | CD44 antigen | P15379.3 |
Cd48 | CD48 antigen | P18181.1 |
Cd69 | early activation antigen CD69 | P37217.1 |
Cd74 | H-2 class II histocompatibility antigen gamma chain | P04441.3 |
Cd80 | T-lymphocyte activation antigen CD80 | Q00609.1 |
Cd83 | CD83 antigen | O88324.1 |
Cr2 | complement receptor type 2 | P19070.1 |
Crp | C-reactive protein | P14847.2 |
Csf1 | macrophage colony-stimulating factor 1 | P07141.2 |
Csf2 | granulocyte-macrophage colony-stimulating factor | P01587.1 |
Csf3 | granulocyte colony-stimulating factor | P09920.1 |
Cxcl5 | C-X-C motif chemokine 5 | P50228.2 |
Cxcl8 | interleukin-8 | P10145.1 |
Cxcr5 | C-X-C chemokine receptor type 5 | Q04683.2 |
Defb4 | beta-defensin 4 | P82019.1 |
Elf3 | ETS-related transcription factor Elf-3 | Q3UPW2.1 |
Eng | endoglin | Q63961.2 |
F3 | tissue factor | P20352.2 |
Fas | tumor necrosis factor receptor superfamily member 6 | P25446.2 |
Faslg | tumor necrosis factor ligand superfamily member 6 | P41047.1 |
Gstp1 | glutathione S-transferase P 1 | P19157.2 |
Hmox1 | heme oxygenase 1 | P14901.1 |
Icam1 | intercellular adhesion molecule 1 | P13597.1 |
Ier3 | radiation-inducible immediate-early gene IEX-1 | P46694.2 |
Ifnb1 | interferon beta | P01575.1 |
Ighg3 | Immunoglobulin heavy constant gamma 3 | P01860.2 |
Ighg4 | Immunoglobulin heavy constant gamma 4 | P01861.1 |
Il11 | interleukin-11 | P47873.1 |
Il13 | interleukin-13 | P20109.1 |
Il15 | interleukin-15 preproprotein | P48346.1 |
Il15ra | interleukin-15 receptor subunit alpha | Q60819.1 |
Il1a | interleukin-1 alpha | P01582.1 |
Il1b | interleukin-1 beta | P10749.1 |
Il1rn | interleukin-1 receptor antagonist protein | P25085.1 |
Il2 | interleukin-2 | Q08867.2 |
Il2ra | interleukin-2 receptor subunit alpha | P01590.1 |
Il6 | interleukin-6 | P08505.1 |
Il9 | interleukin-9 | P15247.1 |
Irf1 | interferon regulatory factor 1 | P15314.1 |
Irf2 | interferon regulatory factor 2 | P23906.1 |
Irf4 | interferon regulatory factor 4 | Q64287.1 |
Irf7 | interferon regulatory factor 7 | P70434.1 |
Klk3 | prostate-specific antigen | P07288.2 |
Lta | lymphotoxin-alpha | P09225.1 |
Ltb | lymphotoxin-beta | P41155.1 |
Mmp9 | matrix metalloproteinase-9 preproprotein | P41245.2 |
Myc | myc proto-oncogene protein | P01108.1 |
Nfkb1 | nuclear factor NF-kappa-B p105 subunit | P25799.2 |
Nfkb2 | nuclear factor NF-kappa-B p100 subunit | Q9WTK5.1 |
Nfkbia | NF-kappa-B inhibitor alpha | Q9Z1E3.2 |
Nod2 | nucleotide-binding oligomerization domain-containing protein 2 | Q8K3Z0.1 |
Nos2 | nitric oxide synthase, inducible | P29477.1 |
Nqo1 | NAD(P)H dehydrogenase [quinone] 1 | Q64669.3 |
Nr4a2 | nuclear receptor subfamily 4 group A member 2 | Q06219.1 |
Oprm1 | mu-type opioid receptor isoform MOR-1B2 | P42866.1 |
Pdgfb | platelet-derived growth factor subunit B | P31240.1 |
Plau | urokinase-type plasminogen activator | P06869.1 |
Plcd1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 | Q8R3B1.2 |
Psma2 | proteasome subunit alpha type-2 | P49722.3 |
Psmb9 | proteasome subunit beta type-9 | O35524.1 |
Ptafr | platelet-activating factor receptor | Q62035.1 |
Ptgs2 | prostaglandin G/H synthase 2 | Q05769.1 |
Ptx3 | pentraxin-related protein PTX3 | P48759.2 |
Relb | transcription factor RelB | Q04863.2 |
S100a6 | protein S100-A6 | P14069.3 |
Scnn1a | amiloride-sensitive sodium channel subunit alpha | Q61180.2 |
Sele | E-selectin | Q00690.1 |
Selp | P-selectin | Q01102.1 |
Slc2a5 | solute carrier family 2, facilitated glucose transporter member 5 | Q9WV38.2 |
Sod2 | superoxide dismutase [Mn], mitochondrial | P09671.3 |
Stat5a | signal transducer and activator of transcription 5A | P42230.1 |
Tacr1 | substance-P receptor | P30548.2 |
Tap1 | antigen peptide transporter 1 | P21958.3 |
Tfpi2 | tissue factor pathway inhibitor 2 | O35536.1 |
Tgm2 | protein-glutamine gamma-glutamyltransferase 2 | P21981.4 |
Tnc | tenascin | Q80YX1.1 |
Tnf | tumor necrosis factor | P06804.2 |
Tnfaip3 | tumor necrosis factor alpha-induced protein 3 | Q60769.2 |
Tnfrsf9 | tumor necrosis factor receptor superfamily member 9 | P20334.1 |
Tp53 | cellular tumor antigen p53 | P02340.4 |
Tpmt | thiopurine S-methyltransferase | Q9QX22.1 |
Vcam1 | vascular cell adhesion protein 1 | P29533.1 |
Vegfc | vascular endothelial growth factor C | P97953.1 |
Vim | vimentin | P20152.3 |
Gene Symbol | Annotation | UniProt Mouse |