National Heart, Lung, and Blood Institute

Epithelial Systems Biology Laboratory (ESBL)


NF-κB Target Genes

This database lists consensus NF-κB target genes from two curated lists at https://www.bu.edu/nf-kb/gene-resources/target-genes/ and http://bioinfo.lifl.fr/NF-KB/.

Database was created by Angela Mak and Mark Knepper in the Epithelial Systems Biology Laboratory (Mark Knepper, Chief) at the National Heart, Lung and Blood Institute as part of its Kidney Systems Biology Project.

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Gene Symbol Annotation UniProt Mouse
Ager advanced glycosylation end product-specific receptor  Q62151.2
Alox12b arachidonate 12-lipoxygenase, 12R-type O70582.1
Apoc3 apolipoprotein C-III   P33622.2
B2m beta-2-microglobulin  P01887.2
Bcl2 apoptosis regulator Bcl-2  P10417.3
Bcl2a1 bcl-2-related protein A1 Q07440.1
Bcl2l1 bcl-2-like protein 1  Q64373.1
Bcl3 B-cell lymphoma 3 protein homolog Q9Z2F6.2
Bdkrb1 B1 bradykinin receptor Q61125.1
Ccl11 eotaxin  P48298.1
Ccl15 C-C motif chemokine 15 preproprotein Q16663.3
Ccl2 C-C motif chemokine 2  P10148.1
Ccl5 C-C motif chemokine 5  P30882.2
Ccnd1 G1/S-specific cyclin-D1  P25322.1
Ccr5 C-C chemokine receptor type 5 P51682.3
Ccr7 C-C chemokine receptor type 7  P47774.2
Cd209 CD209 antigen isoform 8 Q9NNX6.1
Cd3g T-cell surface glycoprotein CD3 gamma chain  P11942.1
Cd40 tumor necrosis factor receptor superfamily member 5   P27512.3
Cd40lg CD40 ligand P27548.2
Cd44 CD44 antigen  P15379.3
Cd48 CD48 antigen   P18181.1
Cd69 early activation antigen CD69 P37217.1
Cd74 H-2 class II histocompatibility antigen gamma chain  P04441.3
Cd80 T-lymphocyte activation antigen CD80  Q00609.1
Cd83 CD83 antigen   O88324.1
Cr2 complement receptor type 2   P19070.1
Crp C-reactive protein  P14847.2
Csf1 macrophage colony-stimulating factor 1   P07141.2
Csf2 granulocyte-macrophage colony-stimulating factor  P01587.1
Csf3 granulocyte colony-stimulating factor  P09920.1
Cxcl5 C-X-C motif chemokine 5  P50228.2
Cxcl8 interleukin-8   P10145.1
Cxcr5 C-X-C chemokine receptor type 5  Q04683.2
Defb4 beta-defensin 4  P82019.1
Elf3 ETS-related transcription factor Elf-3  Q3UPW2.1
Eng endoglin   Q63961.2
F3 tissue factor  P20352.2
Fas tumor necrosis factor receptor superfamily member 6   P25446.2
Faslg tumor necrosis factor ligand superfamily member 6  P41047.1
Gstp1 glutathione S-transferase P 1 P19157.2
Hmox1 heme oxygenase 1 P14901.1
Icam1 intercellular adhesion molecule 1  P13597.1
Ier3 radiation-inducible immediate-early gene IEX-1 P46694.2
Ifnb1 interferon beta  P01575.1
Ighg3 Immunoglobulin heavy constant gamma 3 P01860.2
Ighg4 Immunoglobulin heavy constant gamma 4 P01861.1
Il11 interleukin-11  P47873.1
Il13 interleukin-13  P20109.1
Il15 interleukin-15 preproprotein P48346.1
Il15ra interleukin-15 receptor subunit alpha   Q60819.1
Il1a interleukin-1 alpha P01582.1
Il1b interleukin-1 beta P10749.1
Il1rn interleukin-1 receptor antagonist protein  P25085.1
Il2 interleukin-2  Q08867.2
Il2ra interleukin-2 receptor subunit alpha  P01590.1
Il6 interleukin-6   P08505.1
Il9 interleukin-9  P15247.1
Irf1 interferon regulatory factor 1  P15314.1
Irf2 interferon regulatory factor 2 P23906.1
Irf4 interferon regulatory factor 4  Q64287.1
Irf7 interferon regulatory factor 7  P70434.1
Klk3 prostate-specific antigen  P07288.2
Lta lymphotoxin-alpha  P09225.1
Ltb lymphotoxin-beta P41155.1
Mmp9 matrix metalloproteinase-9 preproprotein P41245.2
Myc myc proto-oncogene protein  P01108.1
Nfkb1 nuclear factor NF-kappa-B p105 subunit P25799.2
Nfkb2 nuclear factor NF-kappa-B p100 subunit  Q9WTK5.1
Nfkbia NF-kappa-B inhibitor alpha Q9Z1E3.2
Nod2 nucleotide-binding oligomerization domain-containing protein 2  Q8K3Z0.1
Nos2 nitric oxide synthase, inducible P29477.1
Nqo1 NAD(P)H dehydrogenase [quinone] 1 Q64669.3
Nr4a2 nuclear receptor subfamily 4 group A member 2 Q06219.1
Oprm1 mu-type opioid receptor isoform MOR-1B2 P42866.1
Pdgfb platelet-derived growth factor subunit B  P31240.1
Plau urokinase-type plasminogen activator  P06869.1
Plcd1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1  Q8R3B1.2
Psma2 proteasome subunit alpha type-2 P49722.3
Psmb9 proteasome subunit beta type-9  O35524.1
Ptafr platelet-activating factor receptor Q62035.1
Ptgs2 prostaglandin G/H synthase 2  Q05769.1
Ptx3 pentraxin-related protein PTX3  P48759.2
Relb transcription factor RelB  Q04863.2
S100a6 protein S100-A6 P14069.3
Scnn1a amiloride-sensitive sodium channel subunit alpha  Q61180.2
Sele E-selectin  Q00690.1
Selp P-selectin  Q01102.1
Slc2a5 solute carrier family 2, facilitated glucose transporter member 5 Q9WV38.2
Sod2 superoxide dismutase [Mn], mitochondrial  P09671.3
Stat5a signal transducer and activator of transcription 5A  P42230.1
Tacr1 substance-P receptor P30548.2
Tap1 antigen peptide transporter 1  P21958.3
Tfpi2 tissue factor pathway inhibitor 2  O35536.1
Tgm2 protein-glutamine gamma-glutamyltransferase 2 P21981.4
Tnc tenascin   Q80YX1.1
Tnf tumor necrosis factor  P06804.2
Tnfaip3 tumor necrosis factor alpha-induced protein 3  Q60769.2
Tnfrsf9 tumor necrosis factor receptor superfamily member 9   P20334.1
Tp53 cellular tumor antigen p53 P02340.4
Tpmt thiopurine S-methyltransferase Q9QX22.1
Vcam1 vascular cell adhesion protein 1  P29533.1
Vegfc vascular endothelial growth factor C P97953.1
Vim vimentin P20152.3

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Gene Symbol Annotation UniProt Mouse