RNA-Seq analysis of aldosterone-sensitive distal tubule cells isolated from mice treated with aldosterone

This database provides median FPKM values for the transcriptome of renal late distal convoluted tubule (DCT2) cells /connecting tubule (CNT) cells/initial cortical collecting duct (iCCD) principal cells from TRPV5 eGFP male mice treated with vehicle or aldosterone for 6 days.

Brief Method: Cells were isolated by FACS from mice expressing EGFP in DCT2 cells, CNT cells and iCCD principal cells. Mice were either treated with vehicle (5% DMSO and physiological saline, n = 7) or aldosterone (100 µg aldosterone kg^-1 24 h^-1 in 5% DMSO and physiological saline, n = 7). RNA was extracted using Qiagen’s RNeasy Micro kit and RNA-Seq libraries were prepared using Illumina’s TruSeq RNA Sample prep kit. Sequencing was performed using a Hiseq 2000 sequencer and obtained sequences were aligned to the UCSC Mus musculus genome index, mm10.

Inclusion Criteria:

control AND aldosterone FPKM values > 0
control OR aldosterone FPKM values > 1
Cufflinks' differential expression analysis Test status = OK

The work was performed at the Department of Biomedicine, Aarhus University, Denmark and the Systems Biology Center, Chulalongkorn University, Thailand. Database is hosted by the Epithelial Systems Biology Laboratory (Mark Knepper, Chief) at the National Heart, Lung and Blood Institute as part of its Kidney Systems Biology Project.

Database Size: 290 transcripts

Download data

Gene symbol	Gene name	Control	Aldosterone	Log₂-ratio (Aldo/Control)	Ratio (Aldo/Control)	p-value	q-value

Mx1	interferon-induced GTP-binding protein Mx1	0.12	3.57	4.92	30.19	0.00016	0.02663
Oasl1	2'-5'-oligoadenylate synthase-like protein 1	0.32	7.44	4.53	23.16	0.00000	0.00000
Ifit1	interferon-induced protein with tetratricopeptide repeats 1	2.19	40.00	4.19	18.23	0.00000	0.00000
Ifit3	interferon-induced protein with tetratricopeptide repeats 3	2.20	35.59	4.02	16.19	0.00000	0.00000
Isg15	-	8.34	118.43	3.83	14.21	0.00000	0.00000
I830012O16Rik	interferon-induced protein with tetratricopeptide repeats 3-like	0.96	11.27	3.55	11.72	0.00000	0.00000
Cxcl10	C-X-C motif chemokine 10 precursor	8.95	99.48	3.47	11.11	0.00000	0.00000
Mx2	interferon-induced GTP-binding protein Mx2	0.40	4.36	3.43	10.78	0.00000	0.00000
Ccl5	C-C motif chemokine 5 precursor	1.29	13.86	3.42	10.73	0.00000	0.00039
Oasl2	2'-5'-oligoadenylate synthase-like protein 2	1.48	13.93	3.24	9.44	0.00000	0.00000
Ifit2	interferon-induced protein with tetratricopeptide repeats 2	1.21	8.22	2.77	6.82	0.00000	0.00000
Ddx60	probable ATP-dependent RNA helicase DDX60	0.29	1.98	2.74	6.70	0.00000	0.00000
Irf7	interferon regulatory factor 7 isoform 3	2.58	17.17	2.73	6.64	0.00000	0.00079
Rsad2	radical S-adenosyl methionine domain-containing protein 2	3.03	18.39	2.60	6.07	0.00000	0.00000
Gbp3	guanylate-binding protein 4	0.72	4.31	2.58	6.00	0.00000	0.00001
Rtp4	receptor-transporting protein 4	1.48	8.42	2.51	5.68	0.00000	0.00001
Ifi47	interferon gamma inducible protein 47	0.89	5.02	2.50	5.65	0.00003	0.00784
AW011738	-	0.47	2.63	2.50	5.65	0.00000	0.00039
Dhx58	probable ATP-dependent RNA helicase DHX58	0.59	3.12	2.40	5.29	0.00000	0.00070
Ifi44	interferon-induced protein 44	0.87	4.50	2.38	5.19	0.00000	0.00001
Cmpk2	UMP-CMP kinase 2, mitochondrial precursor	0.96	4.69	2.29	4.89	0.00000	0.00001
Usp18	ubl carboxyl-terminal hydrolase 18	1.38	6.65	2.26	4.80	0.00000	0.00009
Lgals9	galectin-9 isoform 2	1.07	4.77	2.16	4.46	0.00023	0.03634
Oas1g	2'-5' oligoadenylate synthetase 1G	0.45	1.97	2.13	4.37	0.00027	0.04125
Oas1a	2'-5'-oligoadenylate synthase 1A	1.82	7.53	2.05	4.14	0.00000	0.00013
Tgtp1	T-cell specific GTPase	0.79	3.17	2.01	4.02	0.00001	0.00368
Gbp6	guanylate binding protein 6	0.73	2.91	2.01	4.02	0.00000	0.00030
Atp6v0c-ps2	-	38.45	153.62	2.00	4.00	0.00221	0.22212
Ifitm3	interferon-induced transmembrane protein 3	14.36	56.19	1.97	3.91	0.00000	0.00000
Slc2a6	solute carrier family 2 (facilitated glucose transporter), member 6 isoform 2	0.34	1.33	1.96	3.90	0.00234	0.22920
Iigp1	interferon-inducible GTPase 1	2.51	9.04	1.85	3.60	0.00000	0.00032
Bst2	bone marrow stromal antigen 2 precursor	15.73	55.07	1.81	3.50	0.00000	0.00000
Pcp4	Purkinje cell protein 4	2.83	9.86	1.80	3.48	0.00077	0.09872
Gbp2	interferon-induced guanylate-binding protein 2	1.85	6.39	1.79	3.45	0.00000	0.00051
Oas2	2'-5'-oligoadenylate synthase 2	0.82	2.62	1.68	3.20	0.00005	0.01005
Ckb	creatine kinase B-type	6.86	21.83	1.67	3.18	0.00000	0.00001
Gpx6	glutathione peroxidase 6 precursor	4.02	12.73	1.66	3.17	0.00001	0.00218
Enpp2	ectonucleotide pyrophosphatase/phosphodiesterase family member 2 isoform 4 preproprotein	3.92	10.90	1.48	2.78	0.00000	0.00007
Batf3	basic leucine zipper transcriptional factor ATF-like 3	1.77	4.81	1.44	2.72	0.01535	0.66913
Prodh	proline dehydrogenase 1, mitochondrial precursor	12.49	33.58	1.43	2.69	0.00000	0.00000
Sult1a1	sulfotransferase 1A1	8.62	22.99	1.42	2.67	0.00000	0.00043
Tgtp2	T-cell specific GTPase 2	0.80	2.12	1.40	2.65	0.01097	0.55962
Cend1	cell cycle exit and neuronal differentiation protein 1	0.59	1.53	1.37	2.58	0.02408	0.79280
Fam55c	-	0.69	1.74	1.34	2.53	0.00783	0.48137
Psmb8	proteasome subunit beta type-8 precursor	7.45	18.27	1.29	2.45	0.00005	0.01071
Fkbp5	peptidyl-prolyl cis-trans isomerase FKBP5	15.71	38.47	1.29	2.45	0.00000	0.00002
Xaf1	XIAP-associated factor 1	1.18	2.88	1.28	2.43	0.00327	0.28475
Cited4	cbp/p300-interacting transactivator 4	8.59	20.79	1.27	2.42	0.00003	0.00656
Igtp	interferon gamma induced GTPase	5.64	13.44	1.25	2.38	0.00002	0.00506
Serpina3g	serine protease inhibitor A3G	0.49	1.16	1.23	2.35	0.04658	0.99982
Gbp9	guanylate binding protein family, member 9	0.57	1.33	1.23	2.34	0.01089	0.55962
B2m	beta-2-microglobulin precursor	207.50	486.01	1.23	2.34	0.00000	0.00089
Bdh1	D-beta-hydroxybutyrate dehydrogenase, mitochondrial precursor	13.23	30.90	1.22	2.34	0.00000	0.00010
Cd274	programmed cell death 1 ligand 1 precursor	0.78	1.81	1.21	2.32	0.00617	0.42658
2310042D19Rik	PREDICTED: uncharacterized protein C1orf170 homolog isoform X2	0.53	1.21	1.21	2.31	0.01312	0.61476
Xlr3b	X-linked lymphocyte-regulated protein 3B	2.46	5.69	1.21	2.31	0.00353	0.29630
Hmx2	homeobox protein HMX2	6.12	13.98	1.19	2.28	0.00012	0.02065
Lmcd1	LIM and cysteine-rich domains protein 1	3.17	7.24	1.19	2.28	0.00125	0.14191
Sgk1	serine/threonine-protein kinase Sgk1 isoform a	121.17	271.08	1.16	2.24	0.00298	0.27587
Trim30a	tripartite motif-containing protein 30A	2.80	5.99	1.09	2.14	0.00021	0.03309
Cfb	complement factor B isoform 2 precursor	0.81	1.73	1.09	2.13	0.03728	0.94283
Rorc	nuclear receptor ROR-gamma	6.08	12.73	1.06	2.09	0.00012	0.02065
Parp14	poly [ADP-ribose] polymerase 14	2.22	4.63	1.06	2.09	0.00006	0.01198
Ifih1	interferon-induced helicase C domain-containing protein 1 isoform 2	2.82	5.87	1.06	2.08	0.00010	0.01812
Cwh43	PGAP2-interacting protein	6.76	14.06	1.06	2.08	0.00005	0.01031
Spink8	serine protease inhibitor Kazal-type 8 precursor	147.38	304.04	1.04	2.06	0.00001	0.00234
Glod5	glyoxalase domain-containing protein 5	13.96	28.64	1.04	2.05	0.00199	0.20552
Ube2l6	ubiquitin/ISG15-conjugating enzyme E2 L6	3.93	7.98	1.02	2.03	0.00719	0.46143
Zbtb16	zinc finger and BTB domain-containing protein 16	1.91	3.87	1.02	2.03	0.00107	0.12770
Fabp3	fatty acid-binding protein, heart	25.17	50.38	1.00	2.00	0.00056	0.07513
Il18bp	interleukin-18-binding protein precursor	3.78	7.50	0.99	1.99	0.00959	0.52666
Esrrb	steroid hormone receptor ERR2 isoform 2	1.57	3.07	0.96	1.95	0.04586	0.99982
Tmem163	transmembrane protein 163	1.12	2.17	0.95	1.93	0.03822	0.94579
P2ry1	P2Y purinoceptor 1	1.86	3.59	0.95	1.93	0.00471	0.35228
Lgals3bp	galectin-3-binding protein precursor	14.57	28.01	0.94	1.92	0.00009	0.01736
Adh6a	alcohol dehydrogenase 6A (class V)	2.59	4.97	0.94	1.92	0.03347	0.89666
Lrtm2	leucine-rich repeat and transmembrane domain-containing protein 2 precursor	1.30	2.49	0.94	1.92	0.01748	0.70398
S100a14	protein S100-A14 isoform b	16.83	31.95	0.92	1.90	0.00632	0.42867
Syt7	synaptotagmin-7 gamma isoform	1.42	2.67	0.91	1.88	0.02122	0.77220
Lpl	lipoprotein lipase precursor	18.84	35.32	0.91	1.87	0.00012	0.02096
Mfge8	lactadherin isoform 1 precursor	6.06	11.30	0.90	1.87	0.00944	0.52490
Uba7	ubiquitin-like modifier-activating enzyme 7	2.99	5.58	0.90	1.86	0.00386	0.30913
Pmp22	peripheral myelin protein 22	4.29	7.98	0.89	1.86	0.00848	0.50241
H2-T23	H-2 class I histocompatibility antigen, D-37 alpha chain precursor	20.46	37.99	0.89	1.86	0.00051	0.07069
Mlph	melanophilin	6.84	12.68	0.89	1.85	0.00019	0.03080
Ttc22	tetratricopeptide repeat protein 22	1.26	2.34	0.89	1.85	0.04312	0.99982
Cry1	cryptochrome-1	2.58	4.73	0.88	1.84	0.00960	0.52666
Inmt	indolethylamine N-methyltransferase	9.69	17.77	0.87	1.83	0.00750	0.47624
Cox7a1	cytochrome c oxidase subunit 7A1, mitochondrial precursor	200.46	367.35	0.87	1.83	0.00033	0.04943
Stat1	signal transducer and activator of transcription 1 isoform 2	6.20	11.32	0.87	1.83	0.00121	0.13903
Sult1d1	sulfotransferase 1 family member D1	5.20	9.43	0.86	1.81	0.00320	0.28372
Gbp7	guanylate binding protein 7	0.85	1.55	0.85	1.81	0.02740	0.84248
Pxmp2	peroxisomal membrane protein 2	4.15	7.47	0.85	1.80	0.04616	0.99982
Cdr2	cerebellar degeneration-related protein 2	2.70	4.85	0.85	1.80	0.01456	0.65163
Gadd45g	growth arrest and DNA damage-inducible protein GADD45 gamma	106.25	190.48	0.84	1.79	0.00042	0.05895
Acot11	acyl-coenzyme A thioesterase 11	1.90	3.41	0.84	1.79	0.00483	0.35930
Gchfr	GTP cyclohydrolase 1 feedback regulatory protein	16.34	29.07	0.83	1.78	0.01510	0.66402
Rnaset2b	ribonuclease T2B precursor	157.33	276.63	0.81	1.76	0.00084	0.10601
Mthfd2	bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial precursor	11.06	19.30	0.80	1.74	0.00161	0.17072
Gpr162	probable G-protein coupled receptor 162	7.08	12.28	0.79	1.73	0.00232	0.22920
Irgm1	immunity-related GTPase family M protein 1	13.34	22.99	0.79	1.72	0.00132	0.14400
Ak1	adenylate kinase isoenzyme 1 isoform 2	11.96	20.61	0.79	1.72	0.00378	0.30684
Ppp1r1b	protein phosphatase 1 regulatory subunit 1B	3.53	6.07	0.78	1.72	0.03606	0.93184
Psmb10	proteasome subunit beta type-10 precursor	10.87	18.64	0.78	1.72	0.00757	0.47770
Coro2a	coronin-2A isoform 1	7.72	13.18	0.77	1.71	0.00200	0.20552
Wscd2	WSC domain-containing protein 2	5.09	8.64	0.76	1.70	0.00310	0.28257
Aebp1	adipocyte enhancer-binding protein 1 precursor	7.27	12.30	0.76	1.69	0.00590	0.41048
Ccbl2	kynurenine--oxoglutarate transaminase 3	9.00	15.20	0.76	1.69	0.00338	0.28794
Tmem37	voltage-dependent calcium channel gamma-like subunit	9.48	15.97	0.75	1.68	0.02361	0.79248
Ly6e	lymphocyte antigen 6E precursor	329.87	554.52	0.75	1.68	0.02952	0.86010
Mtfp1	mitochondrial fission process protein 1	11.91	19.99	0.75	1.68	0.00646	0.43124
Ank	progressive ankylosis protein	3.07	5.12	0.74	1.67	0.01575	0.67715
Herc6	E3 ISG15--protein ligase Herc6	4.12	6.87	0.74	1.67	0.00320	0.28372
Tha1	threonine aldolase 1	3.42	5.71	0.74	1.67	0.04427	0.99982
1200009I06Rik	-	5.06	8.43	0.73	1.66	0.00929	0.52313
1810014F10Rik	-	38.72	64.32	0.73	1.66	0.00578	0.41023
H2-K1	H-2 class I histocompatibility antigen, K-W28 alpha chain isoform 1 precursor	207.04	343.87	0.73	1.66	0.00886	0.51382
Gm1332	-	12.61	20.85	0.73	1.65	0.04909	0.99982
Irgm2	interferon inducible GTPase 2	2.35	3.88	0.72	1.65	0.02816	0.84986
Sec14l2	SEC14-like protein 2	2.36	3.88	0.72	1.65	0.04871	0.99982
Prom2	prominin-2 isoform 2 precursor	7.17	11.81	0.72	1.65	0.00462	0.34912
Adra2a	alpha-2A adrenergic receptor	2.09	3.45	0.72	1.65	0.03127	0.87801
Trim12a	tripartite motif-containing protein 12A	8.61	14.13	0.72	1.64	0.01645	0.68376
Ckmt1	creatine kinase U-type, mitochondrial precursor	108.57	178.17	0.71	1.64	0.00309	0.28257
Atp5g1	ATP synthase F(0) complex subunit C1, mitochondrial	327.33	536.75	0.71	1.64	0.01199	0.58940
Fdps	farnesyl pyrophosphate synthase isoform 1 precursor	36.43	59.71	0.71	1.64	0.00263	0.25163
Vars	valine--tRNA ligase	13.59	22.00	0.69	1.62	0.00239	0.23289
Ppa1	inorganic pyrophosphatase	12.36	19.99	0.69	1.62	0.01289	0.61206
Mgll	monoglyceride lipase isoform a	13.70	22.15	0.69	1.62	0.00806	0.49025
Slc26a4	pendrin	63.34	102.25	0.69	1.61	0.00816	0.49118
Ly6a	lymphocyte antigen 6A-2/6E-1 precursor	317.15	511.09	0.69	1.61	0.00706	0.46097
2610029I01Rik	-	5.94	9.57	0.69	1.61	0.03194	0.88391
Tsc22d3	TSC22 domain family protein 3 isoform 2	10.80	17.36	0.68	1.61	0.02156	0.77625
Foxi1	forkhead box protein I1	27.39	43.96	0.68	1.61	0.00360	0.29725
Stmn1	stathmin	13.79	22.10	0.68	1.60	0.02006	0.76313
Crip1	cysteine-rich protein 1	65.65	105.01	0.68	1.60	0.01374	0.63189
Cycs	cytochrome c, somatic	138.04	220.73	0.68	1.60	0.01801	0.71288
Dgcr6	protein DGCR6 isoform 2	17.98	28.64	0.67	1.59	0.00968	0.52843
Alas1	5-aminolevulinate synthase, nonspecific, mitochondrial precursor	23.83	37.92	0.67	1.59	0.00333	0.28702
Lcn2	neutrophil gelatinase-associated lipocalin precursor	18.01	28.64	0.67	1.59	0.03076	0.87001
Ces1d	carboxylesterase 1D precursor	46.47	73.74	0.67	1.59	0.00447	0.34426
Vegfb	vascular endothelial growth factor B isoform Vegf-b167 precursor	29.00	45.92	0.66	1.58	0.03126	0.87801
Ndufs8	NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial	51.02	80.63	0.66	1.58	0.00564	0.40430
Oxct1	succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial precursor	206.96	326.76	0.66	1.58	0.04492	0.99982
Mdh2	malate dehydrogenase, mitochondrial precursor	258.45	407.96	0.66	1.58	0.01401	0.63189
2310061C15Rik	-	8.71	13.69	0.65	1.57	0.02956	0.86010
Uqcrfs1	cytochrome b-c1 complex subunit Rieske, mitochondrial	174.05	273.22	0.65	1.57	0.00912	0.52225
Pycr2	pyrroline-5-carboxylate reductase 2	24.96	39.18	0.65	1.57	0.01572	0.67715
Fxyd2	sodium/potassium-transporting ATPase subunit gamma isoform b	675.64	1059.31	0.65	1.57	0.03540	0.92098
Acot9	acyl-coenzyme A thioesterase 9, mitochondrial	31.36	49.13	0.65	1.57	0.00542	0.39291
Klf15	Krueppel-like factor 15	8.37	13.11	0.65	1.57	0.01483	0.66126
Dagla	sn1-specific diacylglycerol lipase alpha	1.57	2.47	0.65	1.57	0.04632	0.99982
S100a10	protein S100-A10	89.18	139.53	0.65	1.56	0.00650	0.43124
Atp5k	ATP synthase subunit e, mitochondrial	1485.71	2310.98	0.64	1.56	0.00949	0.52547
Apoo	apolipoprotein O isoform 3	91.56	142.07	0.63	1.55	0.03447	0.90749
Akap2	A-kinase anchor protein 2 isoform 1	3.97	6.16	0.63	1.55	0.04186	0.99977
Timm10	mitochondrial import inner membrane translocase subunit Tim10	19.86	30.77	0.63	1.55	0.04440	0.99982
S100a1	protein S100-A1	980.42	1517.60	0.63	1.55	0.03002	0.86080
Stat2	signal transducer and activator of transcription 2	3.42	5.29	0.63	1.55	0.02190	0.77625
Trim34a	tripartite motif-containing protein 34A	5.60	8.63	0.62	1.54	0.02656	0.82734
Pgam2	phosphoglycerate mutase 2	366.95	564.42	0.62	1.54	0.01871	0.73069
Cox5a	cytochrome c oxidase subunit 5A, mitochondrial precursor	341.47	525.22	0.62	1.54	0.01206	0.58940
Bcat2	branched-chain-amino-acid aminotransferase, mitochondrial isoform 2	70.81	108.79	0.62	1.54	0.01075	0.55962
Ndufa10	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial precursor	91.44	140.10	0.62	1.53	0.00796	0.48698
Def6	differentially expressed in FDCP 6	6.11	9.37	0.62	1.53	0.03216	0.88815
Echs1	enoyl-CoA hydratase, mitochondrial precursor	105.64	161.80	0.62	1.53	0.00932	0.52313
Uqcrq	cytochrome b-c1 complex subunit 8	272.55	417.26	0.61	1.53	0.00895	0.51473
Tmem132a	transmembrane protein 132A precursor	13.29	20.33	0.61	1.53	0.00856	0.50241
Ndufb7	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7	134.69	206.00	0.61	1.53	0.00934	0.52313
Atp6v0d2	V-type proton ATPase subunit d 2	37.88	57.93	0.61	1.53	0.01047	0.55086
Gpd1	-	3.89	5.95	0.61	1.53	0.04499	0.99982
Mecr	trans-2-enoyl-CoA reductase, mitochondrial precursor	12.40	18.95	0.61	1.53	0.02747	0.84248
Ndufs3	NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial precursor	160.19	244.62	0.61	1.53	0.01038	0.55086
Acss3	acyl-CoA synthetase short-chain family member 3, mitochondrial isoform 1	16.25	24.80	0.61	1.53	0.02028	0.76409
Abca13	ATP-binding cassette sub-family A member 13	4.91	7.49	0.61	1.53	0.00992	0.53375
Gm11127	predicted gene 11127 precursor	10.13	15.43	0.61	1.52	0.04195	0.99982
Tmem35	transmembrane protein 35	9.47	14.40	0.60	1.52	0.02383	0.79280
Tap1	antigen peptide transporter 1 isoform 2	7.06	10.67	0.60	1.51	0.02191	0.77625
Chchd10	coiled-coil-helix-coiled-coil-helix domain-containing protein 10, mitochondrial	193.00	291.75	0.60	1.51	0.01366	0.63189
Hhatl	protein-cysteine N-palmitoyltransferase HHAT-like protein	42.60	64.34	0.59	1.51	0.00999	0.53513
Aldh1l1	cytosolic 10-formyltetrahydrofolate dehydrogenase	49.13	74.05	0.59	1.51	0.01377	0.63189
Gm17821	-	1.29	1.94	0.59	1.51	0.03734	0.94283
Sqle	squalene monooxygenase	4.27	6.42	0.59	1.50	0.04951	0.99982
Pafah2	platelet-activating factor acetylhydrolase 2, cytoplasmic isoform b	15.09	22.69	0.59	1.50	0.01086	0.55962
H2-D1	H-2 class I histocompatibility antigen, D-B alpha chain precursor	155.16	232.58	0.58	1.50	0.02474	0.80067
Bola3	bolA-like protein 3	62.52	93.64	0.58	1.50	0.02162	0.77625
Idh2	isocitrate dehydrogenase [NADP], mitochondrial precursor	255.43	382.31	0.58	1.50	0.03773	0.94372
Uqcrc1	cytochrome b-c1 complex subunit 1, mitochondrial precursor	148.72	222.57	0.58	1.50	0.02184	0.77625
Mrpl34	39S ribosomal protein L34, mitochondrial	42.83	64.09	0.58	1.50	0.02648	0.82712
Nme2	nucleoside diphosphate kinase B	113.81	169.78	0.58	1.49	0.02839	0.85007
Olfm4	olfactomedin-4 precursor	10.99	16.38	0.58	1.49	0.03669	0.93773
Nme1	nucleoside diphosphate kinase A	31.99	47.69	0.58	1.49	0.01606	0.67715
Tab1	TGF-beta-activated kinase 1 and MAP3K7-binding protein 1	5.43	8.08	0.57	1.49	0.03737	0.94283
Wfdc2	WAP four-disulfide core domain protein 2 precursor	707.51	1052.00	0.57	1.49	0.04893	0.99982
Mrpl45	39S ribosomal protein L45, mitochondrial	9.74	14.48	0.57	1.49	0.02322	0.78837
Mrps16	28S ribosomal protein S16, mitochondrial precursor	65.37	97.05	0.57	1.48	0.02413	0.79280
Cyb561	cytochrome b561	19.05	28.25	0.57	1.48	0.01400	0.63189
0610012G03Rik	-	15.24	22.57	0.57	1.48	0.02943	0.86010
Atp5j2	ATP synthase subunit f, mitochondrial	488.86	723.85	0.57	1.48	0.02070	0.77220
Lynx1	ly-6/neurotoxin-like protein 1 precursor	5.81	8.59	0.56	1.48	0.02496	0.80105
Tufm	elongation factor Tu, mitochondrial isoform 1	49.47	73.10	0.56	1.48	0.01660	0.68532
Pgls	6-phosphogluconolactonase	22.76	33.62	0.56	1.48	0.04116	0.98923
Cox6a1	cytochrome c oxidase subunit 6A1, mitochondrial	721.39	1064.49	0.56	1.48	0.03040	0.86806
Arnt2	aryl hydrocarbon receptor nuclear translocator 2	2.57	3.78	0.56	1.47	0.04324	0.99982
Ndufa11	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11	25.23	37.17	0.56	1.47	0.01641	0.68376
Mrpl12	39S ribosomal protein L12, mitochondrial precursor	72.81	107.24	0.56	1.47	0.01589	0.67715
Nqo1	NAD(P)H dehydrogenase [quinone] 1	11.29	16.63	0.56	1.47	0.04291	0.99982
Mif	macrophage migration inhibitory factor	215.11	316.46	0.56	1.47	0.01599	0.67715
Afm	afamin precursor	13.42	19.74	0.56	1.47	0.02693	0.83659
Ndrg2	protein NDRG2 isoform 2	68.31	100.43	0.56	1.47	0.02322	0.78837
Ndufc2	NADH dehydrogenase [ubiquinone] 1 subunit C2	185.27	272.19	0.55	1.47	0.01690	0.69020
Atp5o	ATP synthase subunit O, mitochondrial precursor	389.63	572.32	0.55	1.47	0.03072	0.87001
Ddt	D-dopachrome decarboxylase	93.04	136.47	0.55	1.47	0.02122	0.77220
Mrpl46	39S ribosomal protein L46, mitochondrial	23.25	34.08	0.55	1.47	0.03450	0.90749
Cox5b	cytochrome c oxidase subunit 5B, mitochondrial	607.28	889.93	0.55	1.47	0.03170	0.87960
Adhfe1	hydroxyacid-oxoacid transhydrogenase, mitochondrial	14.22	20.79	0.55	1.46	0.03383	0.89925
2310061I04Rik	uncharacterized protein LOC69662	36.54	53.36	0.55	1.46	0.02018	0.76409
Psme1	proteasome activator complex subunit 1	70.12	102.37	0.55	1.46	0.02786	0.84301
Gys1	glycogen [starch] synthase, muscle	16.92	24.70	0.55	1.46	0.01659	0.68532
Cyc1	cytochrome c1, heme protein, mitochondrial	244.33	356.46	0.54	1.46	0.03324	0.89628
Atp6v1g3	V-type proton ATPase subunit G 3	62.48	91.11	0.54	1.46	0.02393	0.79280
Gnpda1	glucosamine-6-phosphate isomerase 1	7.58	11.05	0.54	1.46	0.04427	0.99982
Sv2a	synaptic vesicle glycoprotein 2A	12.61	18.37	0.54	1.46	0.01914	0.74262
Gfm1	elongation factor G, mitochondrial	25.35	36.90	0.54	1.46	0.02164	0.77625
1810013D10Rik	-	29.84	43.42	0.54	1.45	0.03310	0.89628
Ddx58	probable ATP-dependent RNA helicase DDX58	9.18	13.35	0.54	1.45	0.01969	0.75394
D10Jhu81e	ES1 protein homolog, mitochondrial precursor	53.91	78.35	0.54	1.45	0.01939	0.74745
Hepacam2	HEPACAM family member 2 precursor	12.55	18.21	0.54	1.45	0.03601	0.93184
Sdhb	succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial precursor	205.68	298.48	0.54	1.45	0.02921	0.86010
Tuba1a	tubulin alpha-1A chain	51.65	74.82	0.53	1.45	0.02091	0.77220
Brp44l	-	143.58	207.91	0.53	1.45	0.02116	0.77220
9830001H06Rik	suppressor of glucose by autophagy	1.48	2.14	0.53	1.45	0.04826	0.99982
Ndufb10	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10	267.53	386.67	0.53	1.45	0.02482	0.80067
Gsto1	glutathione S-transferase omega-1	23.29	33.62	0.53	1.44	0.03615	0.93200
Ndufv2	NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial isoform 2	96.97	139.93	0.53	1.44	0.02612	0.81784
Pcolce	procollagen C-endopeptidase enhancer 1 precursor	55.58	80.20	0.53	1.44	0.02110	0.77220
Gstk1	glutathione S-transferase kappa 1	54.36	78.36	0.53	1.44	0.02542	0.80730
Atp5l	ATP synthase subunit g, mitochondrial	606.67	873.47	0.53	1.44	0.03625	0.93248
Fahd1	acylpyruvase FAHD1, mitochondrial	41.25	59.34	0.52	1.44	0.02284	0.78740
Ndufa8	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8	177.44	255.22	0.52	1.44	0.02378	0.79280
Crat	carnitine O-acetyltransferase	12.45	17.91	0.52	1.44	0.03067	0.87001
Insrr	insulin receptor-related protein precursor	19.88	28.55	0.52	1.44	0.03003	0.86080
Rtn4ip1	reticulon-4-interacting protein 1, mitochondrial precursor	9.68	13.91	0.52	1.44	0.03253	0.89401
Ndufb8	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial precursor	194.31	278.95	0.52	1.44	0.02456	0.80067
Mt1	metallothionein-1	416.44	597.28	0.52	1.43	0.03535	0.92098
Slc25a35	solute carrier family 25 member 35	18.17	26.04	0.52	1.43	0.04985	0.99982
Pcyt2	ethanolamine-phosphate cytidylyltransferase	49.77	71.25	0.52	1.43	0.02416	0.79280
Tomm40	mitochondrial import receptor subunit TOM40 homolog	27.21	38.95	0.52	1.43	0.04337	0.99982
Uqcr11	cytochrome b-c1 complex subunit 10	449.69	643.75	0.52	1.43	0.02956	0.86010
Hint1	histidine triad nucleotide-binding protein 1	109.01	155.91	0.52	1.43	0.02863	0.85308
Coq9	ubiquinone biosynthesis protein COQ9, mitochondrial precursor	60.26	86.06	0.51	1.43	0.02519	0.80413
Rab27a	ras-related protein Rab-27A	11.63	16.61	0.51	1.43	0.03366	0.89754
Gstm1	glutathione S-transferase Mu 1	47.95	68.47	0.51	1.43	0.02832	0.85007
Fh1	fumarate hydratase, mitochondrial precursor	89.17	127.14	0.51	1.43	0.03047	0.86806
Ndufv1	NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial precursor	111.00	158.24	0.51	1.43	0.03332	0.89628
Emx2	homeobox protein EMX2	14.60	20.81	0.51	1.42	0.03135	0.87801
Ndufa1	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1	345.81	492.47	0.51	1.42	0.02958	0.86010
Ndufb5	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial precursor	145.53	207.08	0.51	1.42	0.03239	0.89229
Cryab	alpha-crystallin B chain	72.71	103.46	0.51	1.42	0.02724	0.84248
Epas1	endothelial PAS domain-containing protein 1	4.56	6.49	0.51	1.42	0.04403	0.99982
Ndufb6	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6	248.01	352.43	0.51	1.42	0.02773	0.84301
Aqp4	aquaporin-4	12.11	17.19	0.51	1.42	0.03160	0.87960
Phb	prohibitin	83.58	118.51	0.50	1.42	0.03266	0.89536
Ppif	peptidyl-prolyl cis-trans isomerase F, mitochondrial precursor	24.24	34.37	0.50	1.42	0.03940	0.95872
Atp5e	ATP synthase subunit epsilon, mitochondrial	806.19	1142.49	0.50	1.42	0.04821	0.99982
Ndufc1	NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial precursor	341.61	482.27	0.50	1.41	0.03299	0.89628
Uqcr10	cytochrome b-c1 complex subunit 9	510.37	718.72	0.49	1.41	0.03809	0.94528
Cox7a2	cytochrome c oxidase subunit 7A2, mitochondrial precursor	348.07	490.04	0.49	1.41	0.04998	0.99982
Mrpl4	39S ribosomal protein L4, mitochondrial	22.83	32.13	0.49	1.41	0.04781	0.99982
Suox	sulfite oxidase, mitochondrial precursor	16.89	23.73	0.49	1.40	0.03698	0.94103
Mt2	-	192.31	269.63	0.49	1.40	0.04323	0.99982
Ndufs4	NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial	69.58	97.43	0.49	1.40	0.03600	0.93184
Adsl	adenylosuccinate lyase	13.92	19.48	0.49	1.40	0.04704	0.99982
Idh3g	isocitrate dehydrogenase [NAD] subunit gamma 1, mitochondrial precursor	120.29	168.25	0.48	1.40	0.04063	0.98053
Ndufa9	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial precursor	120.35	168.28	0.48	1.40	0.03874	0.95069
Mccc2	methylcrotonoyl-CoA carboxylase beta chain, mitochondrial	33.07	46.22	0.48	1.40	0.03431	0.90749
Ppp1r1a	protein phosphatase 1 regulatory subunit 1A	33.32	46.56	0.48	1.40	0.04279	0.99982
Pdhx	pyruvate dehydrogenase protein X component, mitochondrial	12.03	16.71	0.47	1.39	0.04998	0.99982
Hspe1	10 kDa heat shock protein, mitochondrial	114.74	159.16	0.47	1.39	0.03870	0.95069
Mcee	methylmalonyl-CoA epimerase, mitochondrial precursor	78.19	108.40	0.47	1.39	0.04605	0.99982
Ndufa3	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3	550.59	762.77	0.47	1.39	0.04350	0.99982
Ndufb9	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9	300.32	415.86	0.47	1.38	0.04980	0.99982
Ndufab1	acyl carrier protein, mitochondrial precursor	134.23	185.69	0.47	1.38	0.04211	0.99982
Dbi	acyl-CoA-binding protein isoform 1	147.69	203.91	0.47	1.38	0.04929	0.99982
Inpp5j	phosphatidylinositol 4,5-bisphosphate 5-phosphatase A	20.76	28.63	0.46	1.38	0.04240	0.99982
C130074G19Rik	uncharacterized protein C1orf115 homolog	29.91	41.20	0.46	1.38	0.04307	0.99982
Aifm1	apoptosis-inducing factor 1, mitochondrial isoform 1 precursor	59.05	81.32	0.46	1.38	0.04594	0.99982
Nudt19	nucleoside diphosphate-linked moiety X motif 19, mitochondrial precursor	25.50	35.10	0.46	1.38	0.04727	0.99982
Gde1	glycerophosphodiester phosphodiesterase 1	45.10	61.95	0.46	1.37	0.04659	0.99982
Gas6	growth arrest-specific protein 6 precursor	40.35	55.17	0.45	1.37	0.04870	0.99982