National Heart, Lung, and Blood Institute

Epithelial Systems Biology Laboratory (ESBL)


Rat Inner Medullary Collecting Duct (IMCD) Membrane Proteins

This protein list has been extracted from the full IMCD proteome found on the IMCD Proteome Database. The list includes both integral-membrane proteins and GPI-linked proteins. The list was reported in Yu et al., 2008, PMID: 18596208. All data are from IMCD cells freshly purified from rat inner medullas. See ESBL Databases for more extensive compendia of IMCD proteins.

This website was created by Brad Yu and Mark Knepper. Contact us with questions or comments: knep@helix.nih.gov. Click to download data.


Protein Annotation Gene Symbol Amino Acid Number Calculated M.W. (Da)
ATP-binding cassette sub-family A member 2 Abca2 2434 270798
bile salt export pump Abcb11 1321 146128
multidrug resistance protein 1 Abcb1b 1275 141092
multidrug resistance-associated protein 4 Abcc4 1325 148734
ATP-binding cassette sub-family C member 9 Abcc9 1545 174175
ATP-binding cassette sub-family F member 1 Abcf1 837 94815
angiotensin-converting enzyme precursor Ace 1313 147263
long-chain-fatty-acid--CoA ligase 4 Acsl4 670 74196
long-chain-fatty-acid--CoA ligase 5 Acsl5 683 76274
serine/threonine-protein kinase receptor R3 precursor Acvrl1 504 54483
disintegrin and metalloproteinase domain-containing protein 10 Adam10 749 83956
disintegrin and metalloproteinase domain-containing protein 17 precursor Adam17 827 68285
disintegrin and metalloproteinase domain-containing protein 7 precursor Adam7 789 86670
adenylate cyclase type 6 isoform 2 Adcy6 1166 130376
adenylate cyclase type 8 Adcy8 1248 139692
adhesion G protein-coupled receptor F5 precursor Adgrf5 1349 146743
adhesion G-protein coupled receptor G2 isoform 1 precursor Adgrg2 1013 106564
adhesion G protein-coupled receptor L2 isoform 1 precursor Adgrl2 1487 163973
agrin precursor Agrn 1940 206431
CD166 antigen precursor Alcam 583 62293
alpha-1,3/1,6-mannosyltransferase ALG2 Alg2 415 47274
alkaline phosphatase, tissue-nonspecific isozyme precursor Alpl 524 53580
aminopeptidase N precursor Anpep 965 106231
aquaporin-2 Aqp2 271 28800
aquaporin-4 isoform 1 Aqp4 323 34349
potassium-transporting ATPase alpha chain 2 a Atp12a 1036 114787
sodium/potassium-transporting ATPase subunit alpha-1 precursor Atp1a1 1023 112924
sodium/potassium-transporting ATPase subunit alpha-2 precursor Atp1a2 1020 112087
sodium/potassium-transporting ATPase subunit alpha-3 Atp1a3 1013 111605
sodium/potassium-transporting ATPase subunit alpha-4 Atp1a4 1028 113874
sodium/potassium-transporting ATPase subunit beta-1 Atp1b1 304 35071
sodium/potassium-transporting ATPase subunit beta-3 Atp1b3 279 31699
sarcoplasmic/endoplasmic reticulum calcium ATPase 1 Atp2a1 994 109279
ATPase, Ca++ transporting, slow twitch 2 isoform a Atp2a2 1043 114637
sarcoplasmic/endoplasmic reticulum calcium ATPase 3 Atp2a3 999 109229
plasma membrane calcium-transporting ATPase 1 Atp2b1 1176 129380
plasma membrane calcium-transporting ATPase 2 Atp2b2 1198 132485
plasma membrane calcium-transporting ATPase 4 Atp2b4 1169 128660
Potassium-transporting ATPase alpha chain 1 (Proton pump) (Gastric H+/K+ ATPase alpha subunit) Atp4a 1034 113977
V-type proton ATPase 116 kDa subunit a isoform 1 Atp6v0a1 838 96125
copper-transporting ATPase 1 Atp7a 1492 161963
basal cell adhesion molecule precursor Bcam 624 64899
basigin isoform 2 precursor Bsg 272 27492
barttin Bsnd 308 33764
voltage-dependent L-type calcium channel subunit alpha-1C Cacna1c 2170 243373
voltage-dependent T-type calcium channel subunit alpha-1G isoform 2 Cacna1g 2255 250176
voltage-dependent calcium channel subunit alpha-2/delta-1 isoform 1 precursor Cacna2d1 1091 120963
calreticulin precursor Calr 416 46349
calnexin precursor Canx 591 65129
carbonic anhydrase 4 precursor Car4 309 30353
caveolin-1 isoform beta Cav1 147 16972
monocyte differentiation antigen CD14 precursor Cd14 372 35335
CD151 antigen Cd151 253 28224
antigen-presenting glycoprotein CD1d precursor Cd1d1 336 36334
CD40 ligand Cd40lg 260 29129
CD48 antigen precursor Cd48 240 22542
CD59 glycoprotein precursor Cd59 126 11418
CD9 antigen Cd9 226 25127
cadherin-1 precursor Cdh1 886 80448
cadherin-16 precursor Cdh16 830 87707
cadherin-23 precursor Cdh23 3317 362802
cadherin EGF LAG seven-pass G-type receptor 2 Celsr2 2919 316993
cadherin EGF LAG seven-pass G-type receptor 3 precursor Celsr3 3313 355822
acetylcholine receptor subunit delta precursor Chrnd 517 56890
chloride channel protein ClC-Ka Clcnka 687 75438
chloride channel protein ClC-Ka Clcnka 687 75554
claudin-4 Cldn4 210 22208
chloride intracellular channel protein 1 Clic1 241 26850
chloride intracellular channel protein 4 Clic4 253 28502
protein canopy homolog 2 precursor Cnpy2 182 18629
cannabinoid receptor 2 isoform 2 Cnr2 410 45032
contactin-1 precursor Cntn1 1021 109189
contactin-associated protein 1 precursor Cntnap1 1381 153822
catechol O-methyltransferase Comt 264 29466
cytochrome c oxidase subunit I (mitochondrion) COX1 514 56806
cytochrome c oxidase subunit II (mitochondrion) COX2 227 25797
cytochrome c oxidase subunit 4 isoform 1, mitochondrial precursor Cox4i1 169
carboxypeptidase D precursor Cpd 1378 148427
carnitine O-palmitoyltransferase 1, liver isoform Cpt1a 773 87995
cytochrome b5 Cyb5a 134 15224
cytochrome b5 type B precursor Cyb5b 146 16134
cytochrome b-245, beta polypeptide Cybb 570 65219
cytochrome P450 1A1 Cyp1a1 524 59280
cytochrome P450 2C70 Cyp2c22 489 56083
cytochrome P450 4B1 Cyp4b1 511 58806
dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1 Dad1 113 12366
dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit precursor Ddost 441 45970
endomucin precursor Emcn 250 24251
ectonucleotide pyrophosphatase/phosphodiesterase family member 1 Enpp1 906 102812
epithelial cell adhesion molecule precursor Epcam 315 33015
endoplasmic reticulum resident protein 29 precursor Erp29 260 25609
extended synaptotagmin-1 Esyt1 1088 121048
protocadherin Fat 2 precursor Fat2 4351 478752
flotillin-1 Flot1 428 47368
sodium/potassium-transporting ATPase subunit gamma isoform b Fxyd2 64 7107
FXYD domain-containing ion transport regulator 4 precursor Fxyd4 87 7041
frizzled-1 precursor Fzd1 642 63642
mannosyl-oligosaccharide glucosidase Gcs1 834 91741
vitamin K-dependent gamma-carboxylase Ggcx 758 87348
Golgi apparatus protein 1 precursor Glg1 1171 130136
glutamate receptor 1 precursor Gria1 907 99657
glutamate receptor ionotropic, kainate 4 precursor Grik4 956 105121
glutamate receptor ionotropic, NMDA 2A precursor Grin2a 1464 162960
glutamate receptor ionotropic, NMDA 2D precursor Grin2d 1323 140314
metabotropic glutamate receptor 4 precursor Grm4 912 98262
olfactory guanylyl cyclase GC-D precursor Gucy2d 1110 114710
potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 Hcn1 910 102291
Huntingtin (Huntington disease protein homolog) (HD protein) Hdh 3120 344617
endoplasmin precursor Hsp90b1 802 90097
5-hydroxytryptamine receptor 2A Htr2a 471 52719
intercellular adhesion molecule 1 precursor Icam1 545 57418
insulin-like growth factor 1 receptor precursor Igf1r 1370 80638
cation-independent mannose-6-phosphate receptor precursor Igf2r 2481 270169
integrin alpha-1 precursor Itga1 1180 127753
integrin alpha-2 precursor Itga2 1178 126350
integrin alpha-3 isoform 1 preproprotein Itga3 1053 113455
integrin alpha-7 precursor Itga7 1135 120651
integrin alpha-V precursor Itgav 1044 112290
integrin beta-1 precursor Itgb1 798 86109
inositol 1,4,5-trisphosphate receptor type 1 isoform 1 Itpr1 2748 312878
inositol 1,4,5-trisphosphate receptor type 2 Itpr2 2701 306929
inositol 1,4,5-trisphosphate receptor type 3 Itpr3 2670 304157
potassium voltage-gated channel subfamily D member 3 isoform 3 precursor Kcnd3 611 67738
potassium voltage-gated channel subfamily H member 5 Kcnh5 988 111699
potassium voltage-gated channel subfamily H member 6 Kcnh6 950 105575
ATP-sensitive inward rectifier potassium channel 1 isoform 1 Kcnj1 391 44818
potassium channel subfamily K member 13 Kcnk13 405 44950
small conductance calcium-activated potassium channel protein 1 Kcnn1 536 59084
potassium voltage-gated channel subfamily KQT member 3 Kcnq3 912 100817
neural cell adhesion molecule L1 precursor L1cam 1255 138229
lysosome-associated membrane glycoprotein 1 precursor Lamp1 407 41846
lysosome-associated membrane glycoprotein 2 precursor Lamp2 411 42429
LETM1 and EF-hand domain-containing protein 1, mitochondrial precursor Letm1 739 70764
lutropin-choriogonadotropic hormone receptor precursor Lhcgr 700 75154
vesicular integral-membrane protein VIP36 precursor Lman2 358 35469
leucyl-cystinyl aminopeptidase isoform 2 Lnpep 916 104439
lipoprotein lipase precursor Lpl 474 50298
low-density lipoprotein receptor-related protein 4 precursor Lrp4 1905 209755
cation-dependent mannose-6-phosphate receptor precursor M6pr 278 28754
Amine oxidase [flavin-containing] A (Monoamine oxidase type A) (MAO-A) Maoa 892 97944
malectin isoform1 precursor MLEC 292 29323
myoferlin Myof 2050 233515
NACHT-, LRR- and PYD-containing protein 6 (PYRIN-containing APAF1-like protein 5-like) (Angiotensin II/vasopressin receptor) Nalp6 900 100139
Neurogenic locus notch homolog protein 1 precursor (Notch 1) Notch1 2548 272684
neurogenic locus notch homolog protein 2 precursor Notch2 2471 262498
neurogenic locus notch homolog protein 3 precursor Notch3 2319 240040
atrial natriuretic peptide receptor 1 precursor Npr1 1057 115840
neuropilin-1 precursor Nrp1 922 101032
oxidation resistance 1 Oxr1 873 96891
protein disulfide-isomerase precursor P4hb 509 54983
prenylcysteine oxidase precursor Pcyox1 504 53541
protein disulfide-isomerase A3 precursor Pdia3 505 54206
protein disulfide-isomerase A4 precursor Pdia4 643 70216
protein disulfide-isomerase A6 precursor Pdia6 445 46193
protein disulfide-isomerase A6 precursor Pdia6 445 46193
membrane-associated progesterone receptor component 1 Pgrmc1 223 24534
membrane-associated progesterone receptor component 2 Pgrmc2 217 23272
GPI transamidase component PIG-S Pigs 555 61593
proteolipid protein 2 Plp2 151 16425
plasmalemma vesicle-associated protein Plvap 438 49902
podocalyxin precursor Podxl 485 49111
lipid phosphate phosphohydrolase 3 Ppap2b 312 35102
peripherin-2 Prph2 346 39137
prostaglandin F2-alpha receptor Ptgfr 366 40524
prostaglandin F2 receptor negative regulator precursor Ptgfrn 879 96544
redox-regulatory protein FAM213A RGD1309676 229 25632
dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 precursor Rpn1 606 66073
dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 precursor Rpn2 631 66932
RT1 class Ia, locus A2 precursor RT1-A2 366 39025
class I histocompatibility antigen, Non-RT1.A alpha-1 chain precursor RT1-EC2 319 34078
reticulon-4 Rtn4 1163 126257
sphingosine 1-phosphate receptor 5 S1pr5 400 42238
secretory carrier-associated membrane protein 1 Scamp1 338 37898
secretory carrier-associated membrane protein 2 Scamp2 329 36419
secretory carrier-associated membrane protein 3 isoform 2 Scamp3 349 38327
lysosome membrane protein 2 precursor Scarb2 478 51349
sodium channel protein type 11 subunit alpha Scn11a 1765 201715
sodium channel protein type 4 subunit alpha Scn4a 1840 208737
sodium channel protein type 5 subunit alpha isoform 1 Scn5a 2019 227237
sodium channel protein type 9 subunit alpha Scn9a 1984 225909
signal peptidase complex catalytic subunit SEC11A Sec11a 179 20495
semaphorin-6C precursor Sema6c 960 100088
sideroflexin-3 Sfxn3 321 35302
sphingosine-1-phosphate lyase 1 Sgpl1 568 63627
solute carrier family 12 member 5 Slc12a5 1116 123433
urea transporter 2 isoform 1 Slc14a2 929 101767
monocarboxylate transporter 2 Slc16a7 489 52912
mitochondrial 2-oxoglutarate/malate carrier protein Slc25a11 314
mitochondrial 2-oxoglutarate/malate carrier protein Slc25a11 314
phosphate carrier protein, mitochondrial isoform 2 precursor Slc25a3 356 34828
ADP/ATP translocase 1 Slc25a4 298 32858
ADP/ATP translocase 2 Slc25a5 298 32770
solute carrier family 2, facilitated glucose transporter member 1 Slc2a1 492 53832
band 3 anion transport protein Slc4a1 928 103113
sodium/glucose cotransporter 1 Slc5a1 665 72936
sodium-dependent dopamine transporter Slc6a3 619 68615
sodium- and chloride-dependent taurine transporter Slc6a6 621 69738
sodium/hydrogen exchanger 2 isoform 2 Slc9a2 697 78932
sortilin-related receptor, LDLR class A repeats-containing Sorl1 1811 201899
sortilin 1 isoform 2 Sort1 858 94598
signal peptidase complex subunit 2 Spcs2 226 24847
squalene monooxygenase Sqle 573 63893
translocon-associated protein subunit alpha precursor Ssr1 287 29831
translocon-associated protein subunit delta precursor Ssr4 173 16796
suppression of tumorigenicity 14 St14 827 91888
syntaxin-12 Stx12 274 31056
syntaxin 16 isoform b Stx16 309 35310
syntaxin-5 Stx5 355 39620
syntaxin-7 Stx7 261 29720
syntaxin-8 Stx8 236 26780
synaptogyrin-2 Syngr2 234 25578
synaptophysin-like protein 1 Sypl1 258 28497
synaptotagmin-13 Syt13 426 46750
synaptotagmin-like protein 5 Sytl5 753 83514
very-long-chain enoyl-CoA reductase Tecr 308 35992
transferrin receptor Tfrc 760 85615
TGF-beta receptor type-1 precursor Tgfbr1 497 52722
trans-Golgi network integral membrane protein TGN38 precursor Tgoln2 357 36508
thy-1 membrane glycoprotein preproprotein Thy1 161 12759
transmembrane 9 superfamily member 2 precursor Tm9sf2 663 72678
transmembrane emp24 domain-containing protein 10 precursor Tmed10 219 21748
transmembrane emp24 domain-containing protein 2 precursor Tmed2 201 20781
transmembrane emp24 domain-containing protein 4 precursor Tmed4 227 23193
transmembrane protein 16F Tmem16f 918 106802
Transmembrane protease, serine 9 (Polyserase-1) (Polyserine protease 1) (Polyserase-I) Tmprss9 1103 118514
transient receptor potential cation channel subfamily M member 8 Trpm8 1104 127498
hamartin Tsc1 1163 128892
tuberin Tsc2 1809 201148
tyrosine-protein kinase receptor TYRO3 precursor Tyro3 880 92807
UDP-glucose:glycoprotein glucosyltransferase 1 precursor Uggt1 1527 172205
uromodulin precursor Umod 644 65218
vesicle-associated membrane protein 2 Vamp2 116 12560
vesicle-associated membrane protein 3 Vamp3 103 11349
vesicle-associated membrane protein-associated protein A Vapa 249 27710
vesicle-associated membrane protein-associated protein B Vapb 243 26785
voltage-dependent anion-selective channel protein 1 Vdac1 283 30624
voltage-dependent anion-selective channel protein 2 Vdac2 295 31615
voltage-dependent anion-selective channel protein 3 Vdac3 283 30667
vesicle transport through interaction with t-SNAREs homolog 1A Vti1a 217 25030
palmitoyltransferase ZDHHC7 Zdhhc7 308 35100

Rat Inner Medullary Collecting Duct Membrane Protein Database is hosted and supported by:


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