This database of mpkCCD nuclear proteins is based on protein mass spectrometry data from the NHLBI Epithelial Systems Biology Laboratory (ESBL). All data are from cultured mpkCCD clone 11 cells. This clonal line was developed to maximize AQP2 response to the vasopressin analog 1-desamino-8-D-arginine vasopressin (dDAVP) both in terms of membrane trafficking and transcription. Please cite: Bolger SJ et al. Quantitative phosphoproteomics in nuclei of vasopressin-sensitive renal collecting duct cells. Am J Physiol Cell Physiol. 2012; 303: C1006-20. PMID: 22992673.

Brief methods: mpkCCD cells (clone 11) were fractionated using the commercially available NE-PER kit (Thermo Scientific) yielding the nuclear extract (NE) and nuclear pellet (NP). Protein samples were reduced, alkylated, and digested with trypsin, and the resulting peptides were separated into 24 fractions using strong cation exchange chromatography. The fractionated samples were dried in vacuo and resuspended in 0.1 % formic acid. Phosphopeptides were enriched using Fe-NTA phosphopeptide IMAC columns, and dried samples were resuspended in 0.1% formic acid and desalted using Graphite Spin columns before analysis by LC-MS/MS. Tryptic peptides were analyzed on an LTQ Orbitrap Velos mass spectrometer equipped with a nano-electrospray ion source. The peptides were fractionated with a reversed-phase PicoFrit column using a linear gradient of 5%–35% ACN in 0.1% FA in 45 min at a flow rate of 0.25 μl/min. Precursor mass spectra (MS1) were acquired in the orbitrap at 60,000 resolution and product mass spectra (MS2) were acquired with the ion trap.

This website was created by Steven Bolger, Trairak Pisitkun, Fahad Saeed and Mark Knepper. Contact us with questions or comments: knep@helix.nih.gov

Database updated: May 2, 2012 (download data)

Sort database by: Phospho Abundance Change Total Abundance Change Gene Symbol Protein Name

Notations: * = Phosphorylated amino acid. ^ = Ambiguous phosphorylation site assignment. † = p<0.05 for n>=3. SEM and p-values can be obtained from the full spreadsheet available here. Phosphorylation site certainty was determined based on the PhosSA for SEQUEST search algorithm and/or the Phosphate Localization Score (PLS) for the InsPecT search algorithm.

Nuclear Fraction	Gene Symbol	Protein Name	RefSeq	Peptide	Phosphorylation Site	Log2(dDAVP/vehicle)
						Phospho	Total
NP	Clmn	calmin isoform b	NP_001035772	TGS*IAEPTPESSILSTR	S397^	5.08†	0.07
NP	Sec22b	vesicle-trafficking protein SEC22b precursor	NP_035472	NLGS*INTELQDVQR	S137	3.92†	-0.12
NP	Itpr3	inositol 1,4,5-trisphosphate receptor type 3	NP_542120	VSS*FSMPSSSR	S1832	2.49†	0.10
NP	Ctnnd1	catenin delta-1 isoform 1	NP_031641	SQSS*HSYDDSTLPLIDR	S862	2.23†	0.26†
NP	Hist1h1d	histone H1.3	NP_663759	KAS*GPPVSELITK	S37	2.23†	-0.01
NP	Hist1h1d	histone H1.3	NP_663759	KASGPPVS*ELITK	S42^	2.12†	-0.01
NE	Krt19	keratin, type I cytoskeletal 19	NP_032497	GGS*FSGTLAVSDGLLSGNEK	S67	2.00†	-0.01
NP	Ctnnb1	catenin beta-1	NP_031640	RT*SMGGTQQQFVEGVR	T551	1.83†	0.12
NP	Ctnnb1	catenin beta-1	NP_031640	RTS*MGGTQQQFVEGVR	S552^	1.79†	0.12
NP	Ctnnd1	catenin delta-1 isoform 1	NP_031641	SQSSHS*YDDSTLPLIDR	S864	1.78†	0.26†
NP	Cbx5	chromobox protein homolog 5	NP_031652	KSS*FSNSADDIK	S93	1.62†	-0.01
NP	Aqp2	aquaporin-2	NP_033829	RQS*VELHSPQSLPR	S256	1.50†	N/A
NP	Krt19	keratin, type I cytoskeletal 19	NP_032497	GGS*FSGTLAVSDGLLSGNEK	S67	1.50†	-0.01
NP	Nop56	nucleolar protein 56	NP_077155	KFS*EEPEVAANFTK	S554	1.50†	-0.05
NP	Cbx5	chromobox protein homolog 5	NP_031652	S*SFSNSADDIK	S92	1.44†	-0.01
NP	Hist1h1e	histone H1.4	NP_056602	KTS*GPPVSELITK	S36^	1.09†	-0.05
NE	Srcin1	SRC kinase signaling inhibitor 1	NP_061361	RGS*DELTVPR	S1021	1.08†	0.14
NP	Srcin1	SRC kinase signaling inhibitor 1	NP_061361	RGS*DELTVPR	S1021	0.96†	0.16
NP	Ahnak	AHNAK nucleoprotein isoform 1	NP_033773	AS*LGSLEGEVEAEASSPK	S5522	0.86†	0.15†
NP	Lmna	prelamin-A/C isoform A	NP_001002011	GS*HCSGSGDPAEYNLR	S570	0.81†	0.00
NE	Tcof1	treacle protein isoform 2	NP_035682	KLS*GDLEAGAPK	S1191	0.81†	-0.22
NP	Ahnak	AHNAK nucleoprotein isoform 1	NP_033773	ASLGS*LEGEVEAEASSPK	S5525	0.79†	0.15†
NE	Ahnak	AHNAK nucleoprotein isoform 1	NP_033773	ASLGS*LEGEVEAEASSPK	S5525	0.77†	0.12
NP	Fam82a2	regulator of microtubule dynamics protein 3	NP_001028308	SHS*LPNSLDYAQASER	S46	0.77†	-0.02
NE	Srrm1	serine/arginine repetitive matrix protein 1 isoform 1	NP_058079	S*PSPAPPPPPPPPPPR	S572	0.72†	-0.04
NE	Ahnak	AHNAK nucleoprotein isoform 1	NP_033773	AS*LGSLEGEVEAEASSPK	S5522	0.70†	0.12
NP	Ctdspl2	CTD small phosphatase-like protein 2	NP_997615	KYS*EVDDSLPSGGEKPSK	S28	0.69	0.07†
NE	Ppl	periplakin	NP_032935	S*IVVIDPDTGR	S1655	0.66	-0.04
NP	Hnrnpk	heterogeneous nuclear ribonucleoprotein K	NP_079555	GS*YGDLGGPIITTQVTIPK	S379^	0.63†	-0.01
NP	Jup	junction plakoglobin	NP_034723	RVS*VELTNSLFK	S665	0.60†	0.16†
NP	Tjp3	tight junction protein ZO-3	NP_038797	S*SGGGSEANGLDLVSGYK	S156	0.59†	0.14†
NP	Hist1h1e	histone H1.4	NP_056602	T*SGPPVSELITK	T35^	0.58†	-0.05
NE	Eif4b	eukaryotic translation initiation factor 4B	NP_663600	T*GSESSQTGASATSGR	T420	0.57	N/A
NP	Tjp3	tight junction protein ZO-3	NP_038797	RSS*GGGSEANGLDLVSGYK	S157^	0.57†	0.14†
NE	Eif4b	eukaryotic translation initiation factor 4B	NP_663600	TGS*ESSQTGASATSGR	S422	0.54	N/A
NP	Ncbp1	nuclear cap-binding protein subunit 1	NP_001028373	KTS*DANETEDHLESLICK	S22	0.51	-0.12
NP	Tcof1	treacle protein isoform 2	NP_035682	KLS*GDLEAGAPK	S1191	0.51	-0.20
NE	Krt20	keratin, type I cytoskeletal 20	NP_075745	SLS*SSSQGPALSMSGSLYR	S13	0.51†	-0.02
NP	Ctnna2	catenin alpha-2 isoform 1	NP_663785	T*SVQTEDDQLIAGQSAR	T653	0.49	-0.53
NP	Pnn	pinin	NP_032917	GFS*DSGGGPPAK	S66	0.46	-0.09†
NP	Ctnna2	catenin alpha-2 isoform 1	NP_663785	SRTS*VQTEDDQLIAGQSAR	S654	0.46†	-0.53
NP	Pkp2	plakophilin-2	NP_080439	LEIS*PDSSPER	S151	0.44†	0.00
NE	Srrm2	serine/arginine repetitive matrix protein 2	NP_780438	NSGPVSEVNTGFS*PEVK	S1209	0.43	0.07
NP	Lrrfip2	leucine-rich repeat flightless-interacting protein 2 isoform 2	NP_082018	RGS*GDTSSLIDPDTSLSELR	S96	0.43†	N/A
NP	Akap1	A-kinase anchor protein 1, mitochondrial	NP_033778	RLS*EEACPGVLSVAPTVTQPPGR	S55	0.41†	0.17
NP	Fam83h	protein FAM83H	NP_598848	RGS*LTFAGESSK	S970	0.41†	0.08
NP	Usp14	ubiquitin carboxyl-terminal hydrolase 14 isoform 1	NP_067497	AS*GEMASAQYITAALR	S143	0.39	0.15
NE	1200014J11Rik	uncharacterized protein C17orf85 homolog	NP_080094	AEAPAGPALGLPS*PEVESGLER	S25	0.39	-0.09
NP	C77080	uncharacterized protein KIAA1522	NP_001028361	GS*PSGGSTAETSDTASIR	S459	0.39†	0.17
NP	Tjp1	tight junction protein ZO-1 isoform 1	NP_033412	S*REDLSAQPVQTK	S617	0.38	0.09†
NP	Synpo	synaptopodin isoform A	NP_796314	S*PTDSDVSLDSEDSGLK	S852	0.37†	0.86†
NP	Rai14	ankycorbin	NP_109615	S*SPPVEHPAGTSTTDNDVIIR	S413	0.36†	0.04
NP	Polr2a	DNA-directed RNA polymerase II subunit RPB1	NP_033115	YSPTS*PTYSPTSPK	S1875^	0.35	-0.10
NP	Trp53bp1	tumor suppressor p53-binding protein 1	NP_038763	DAVTEDS*PQPPLPSVR	S822	0.34	-0.09
NE	Raly	RNA-binding protein Raly short isoform	NP_001132984	LPAPQEDT*ASEAGTPQGEVQTR	T252	0.34†	-0.08
NP	Srrm2	serine/arginine repetitive matrix protein 2	NP_780438	SGT*PPRPGSVTNMQADECTATPQR	T727	0.34†	0.13
NE	Canx	calnexin precursor	NP_031623	AEEDEILNRS*PR	S582	0.33	N/A
NE	Trp53bp1	tumor suppressor p53-binding protein 1	NP_038763	DAVTEDS*PQPPLPSVR	S822	0.33	-0.21
NE	Raly	RNA-binding protein Raly short isoform	NP_001132984	LPAPQEDTAS*EAGTPQGEVQTR	S254	0.31†	-0.08
NP	Srrm2	serine/arginine repetitive matrix protein 2	NP_780438	RSS*SELSPEVVEK	S1243	0.31†	0.13
NP	Polr2a	DNA-directed RNA polymerase II subunit RPB1	NP_033115	YSPTS*PTYSPTTPK	S1840	0.29	-0.10
NE	Tjp2	tight junction protein ZO-2 isoform 2	NP_035727	DAS*PPPAFKPEPPK	S968	0.29†	0.40†
NE	Cobll1	cordon-bleu protein-like 1 isoform 1	NP_795999	TGS*LQLSSTSIGTSSLK	S352^	0.28	-0.07
NP	Mecp2	methyl-CpG-binding protein 2 isoform 1	NP_001075448	AETSESSGSAPAVPEASAS*PK	S97	0.28	0.03
NP	Tjp2	tight junction protein ZO-2 isoform 2	NP_035727	VQVAPLQGS*PPLSHDDR	S107	0.28	0.35†
NP	Ctnnb1	catenin beta-1	NP_031640	RLS*VELTSSLFR	S675	0.28†	0.12
NE	Lad1	ladinin-1	NP_598425	LPS*VEEAEVSKPSPPASKDEDEDFQAILR	S62	0.27	-0.01
NE	Srrm1	serine/arginine repetitive matrix protein 1 isoform 1	NP_058079	RRS*PS*PAPPPPPPPPPPR	S572, S574	0.27	-0.04
NP	Raly	RNA-binding protein Raly short isoform	NP_001132984	LPAPQEDTAS*EAGTPQGEVQTR	S254	0.27†	-0.07†
NP	Tjp2	tight junction protein ZO-2 isoform 2	NP_035727	DAS*PPPAFKPEPPK	S968	0.26†	0.35†
NE	Trip12	thyroid hormone receptor interactor 12	NP_598736	SES*PPAELPSLR	S312	0.25	0.04
NP	Nup35	nucleoporin NUP53 isoform 1	NP_081367	TLGT*PTQSGSTPR	T272	0.24	1.74
NP	Snip1	smad nuclear-interacting protein 1	NP_780455	S*GDALTTVVVK	S18	0.24	N/A
NE	C77080	uncharacterized protein KIAA1522	NP_001028361	GS*PSGGSTAETSDTASIR	S459	0.24	0.02
NP	Sec62	translocation protein SEC62	NP_081292	GAPADHGPEGS*GGER	S335	0.23	0.27
NP	Ptpn14	tyrosine-protein phosphatase non-receptor type 14	NP_033002	ICTEQSNS*PPPIR	S314	0.22	0.35
NE	Tmpo	lamina-associated polypeptide 2 isoform alpha	NP_035735	LSQSSYQDSESLS*PPR	S422	0.22†	-0.05
NE	Ddx21	nucleolar RNA helicase 2	NP_062426	EIITEEPS*EEEADMPKPK	S118	0.22†	-0.09
NP	Krt20	keratin, type I cytoskeletal 20	NP_075745	SLSSSS*QGPALSMSGSLYR	S16^	0.19	0.01
NP	Plekha6	pleckstrin homology domain-containing family A member 6 isoform 1	NP_891846	S*PAEEELTPSAVVR	S901	0.19	0.22†
NP	Sf3b2	splicing factor 3b, subunit 2	NP_084385	S*SLGQSASETEEDTVSISK	S285^	0.19	-0.08
NE	Dido1	death-inducer obliterator 1 isoform 2	NP_808520	S*PPEGDTTLFLSR	S1035	0.18	-0.10
NP	Krt20	keratin, type I cytoskeletal 20	NP_075745	SLS*SSSQGPALSMSGSLYR	S13	0.18	0.01
NP	Tmpo	lamina-associated polypeptide 2 isoform alpha	NP_035735	LSQSSYQDSESLS*PPR	S422	0.17	-0.07
NP	Srrm1	serine/arginine repetitive matrix protein 1 isoform 1	NP_058079	S*PS*PAPPPPPPPPPPR	S572, S574	0.17	0.12
NP	Mtap2	microtubule-associated protein 2 isoform 1	NP_001035023	VDHGAEIITQS*PSR	S453	0.16	N/A
NP	Svil	supervillin	NP_694793	RGS*LELGNPSAAHLGDELK	S960	0.16	-0.07
NP	Ssfa2	sperm-specific antigen 2 homolog	NP_542125	SQS*LPTTLLSPVR	S738	0.16†	N/A
NP	Brd1	bromodomain containing 1	NP_001028446	IVEYS*PPSAPR	S128	0.15	0.02
NP	Tjp3	tight junction protein ZO-3	NP_038797	ASPASGHQLS*DQEEADHGR	S111	0.15	0.14†
NP	Srrm1	serine/arginine repetitive matrix protein 1 isoform 1	NP_058079	S*PSPAPPPPPPPPPPR	S572	0.15†	0.12
NP	Srrm2	serine/arginine repetitive matrix protein 2	NP_780438	SSS*PVTELTAR	S972	0.15†	0.13
NE	Bod1l	biorientation of chromosomes in cell division 1-like	NP_001074891	TETDITTVEQSS*PSGK	S2841	0.14	0.36
NP	Ddx21	nucleolar RNA helicase 2	NP_062426	EIITEEPS*EEEADMPKPK	S118	0.14†	0.07
NP	Srrm2	serine/arginine repetitive matrix protein 2	NP_780438	SEQPLSQVLPSLS*PEHK	S1120	0.14†	0.13
NE	Srrm2	serine/arginine repetitive matrix protein 2	NP_780438	SS*SPVTELTAR	S971^	0.14†	0.07
NP	Brd3	bromodomain-containing protein 3 isoform 2	NP_075825	SES*PPPLSEPK	S262	0.13	N/A
NP	Polr2a	DNA-directed RNA polymerase II subunit RPB1	NP_033115	YSPTSPTYSPTS*PK	S1882	0.13	-0.10
NE	Tmpo	lamina-associated polypeptide 2 isoform delta	NP_001073599	SSTPLPTVS*SSAENTR	S165	0.13	0.03
NP	Srrm2	serine/arginine repetitive matrix protein 2	NP_780438	VSS*PVLETVQQR	S1264	0.13†	0.13
NP	Baz1b	tyrosine-protein kinase BAZ1B	NP_035844	LADDEGDS*DSESVGQSR	S1464	0.13†	-0.02
NP	Cdk2	cyclin-dependent kinase 2 isoform 2	NP_058036	IGEGTY*GVVYK	Y15^	0.12	N/A
NP	Dot1l	histone-lysine N-methyltransferase, H3 lysine-79 specific	NP_955354	AAATEAPADS*GAEEEK	S373	0.12	N/A
NP	Klf3	Krueppel-like factor 3	NP_032479	GS*PPAAGGSPSSLK	S71	0.12	N/A
NP	Lima1	LIM domain and actin-binding protein 1 isoform b	NP_075550	PAQPPNAGESPHS*PGVEDAPIAK	S328	0.12	0.07
NP	Pcm1	pericentriolar material 1 protein	NP_076151	VTNAIS*PESSPGVGR	S65	0.12	0.15
NP	Mki67	antigen KI-67	NP_001074586	LPSS*SPPLEPTDTSVTSR	S2424	0.11	0.04
NP	Bclaf1	bcl-2-associated transcription factor 1 isoform 2	NP_722482	ELFDYS*PPLHK	S508	0.11	-0.12†
NP	Dcaf8	DDB1- and CUL4-associated factor 8	NP_705783	GHGHS*DEEDEEQPR	S100	0.11	N/A
NP	Srrm2	serine/arginine repetitive matrix protein 2	NP_780438	SS*SPVTELTAR	S971^	0.11	0.13
NE	Hdgf	hepatoma-derived growth factor	NP_032257	AGDVLEDS*PK	S165	0.11†	0.06
NP	Scrib	protein scribble homolog	NP_598850	NS*LESISSIDR	S1206	0.11†	0.13†
NP	Bckdk	[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial precursor	NP_033869	S*TSATDTHHVELAR	S31^	0.10	N/A
NE	Foxk2	forkhead box protein K2	NP_001074401	EGS*PAPLEPEPGASQPK	S389	0.10	N/A
NP	Hnrnpc	heterogeneous nuclear ribonucleoproteins C1/C2 isoform 2	NP_001164452	NEKS*EEEQSSASVK	S228	0.10	-0.10†
NP	Scaf11	splicing factor, arginine/serine-rich 2, interacting protein	NP_082424	ETVVESQSSQS*PS*PK	S857, S859	0.10	0.06
NE	Tcf20	transcription factor 20 isoform b	NP_038864	AGSS*PTQGAQNEAPR	S588	0.10	N/A
NP	Srrm2	serine/arginine repetitive matrix protein 2	NP_780438	VS*SPVLETVQQR	S1263	0.10†	0.13
NP	Srsf6	arginine/serine-rich splicing factor 6	NP_080775	SHS*PLPAPPSK	S303	0.09	0.04
NP	LOC100044391	PREDICTED: non-histone chromosomal protein HMG-14-like	XP_001472107	QADVADQQTTELPAENGETENQSPAS*EEEK	S87^	0.09	-0.03
NE	G3bp1	ras GTPase-activating protein-binding protein 1	NP_038744	S*TSPAPADVAPAQEDLR	S229	0.09	-0.02
NE	Tcea1	transcription elongation factor A protein 1 isoform 2	NP_035671	EPAISSQNS*PEAR	S100	0.09	0.13
NP	Hist1h1b	histone H1.5	NP_064418	SETAPAETAAPAPVEKS*PAK	S18	0.08	-0.01
NP	Nop58	nucleolar protein 58	NP_061356	EEPLS*EEEPCTSTAVPS*PEK	S509, S521	0.08	-0.05
NP	LOC100044829	PREDICTED: rRNA 2'-O-methyltransferase fibrillarin-like isoform 1	XP_001472922	RVS*ISEGDDKIEYR	S130	0.08	-0.07
NE	Fip1l1	pre-mRNA 3'-end-processing factor FIP1 isoform 2	NP_077145	DHS*PTPSVFNSDEER	S443	0.08	-0.07
NP	Srrm2	serine/arginine repetitive matrix protein 2	NP_780438	NSGPVSEVNTGFS*PEVK	S1209	0.08	0.13
NP	Dyrk1b	dual specificity tyrosine-phosphorylation-regulated kinase 1B isoform a	NP_034222	IYQY*IQSR	Y273^	0.08†	N/A
NE	Hnrnpc	heterogeneous nuclear ribonucleoproteins C1/C2 isoform 2	NP_001164452	NEKS*EEEQSSASVK	S228	0.08†	-0.06
NP	Api5	apoptosis inhibitor 5	NP_031492	TSEDTSSGS*PPK	S464	0.07	0.04
NP	Ctnnd1	catenin delta-1 isoform 1	NP_031641	VGGS*SVDLHR	S268	0.07	0.26†
NE	Mybbp1a	myb-binding protein 1A	NP_058056	SPAPSNPTLS*PSTPAK	S1253	0.07	-0.10
NE	Snip1	smad nuclear-interacting protein 1	NP_780455	S*GDALTTVVVK	S18	0.07	N/A
NE	Supt5h	transcription elongation factor SPT5	NP_038704	DVTNLTVGGFTPMS*PR	S664	0.07	-0.24
NP	Bckdk	[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial precursor	NP_033869	ST*SATDTHHVELAR	T32^	0.06	N/A
NP	LOC100046628	PREDICTED: nucleophosmin-like	XP_001476579	DELHIVEAEAMNYEGS*PIKVTLATLK	S70	0.06	-0.02
NE	Rbm39	RNA-binding protein 39	NP_573505	DKS*PVREPIDNLTPEER	S136	0.06	-0.13
NE	Srrm1	serine/arginine repetitive matrix protein 1 isoform 1	NP_058079	EKS*PELPEPSVR	S220	0.06	-0.04
NE	Tcf20	transcription factor 20 isoform b	NP_038864	AGS*SPTQGAQNEAPR	S587	0.06	N/A
NP	Vdac1	voltage-dependent anion-selective channel protein 1	NP_035824	KLTFDSSFS*PNTGK	S104	0.06	-0.01
NP	Rps3	40S ribosomal protein S3	NP_036182	DEILPTT*PISEQK	T221	0.05	0.13†
NP	Tmpo	lamina-associated polypeptide 2 isoform delta	NP_001073599	SS*TPLPTVSSSAENTR	S158^	0.05	0.02
NP	Tmpo	lamina-associated polypeptide 2 isoform delta	NP_001073599	S*STPLPTVSSSAENTR	S157	0.05	0.02
NP	Nup205	nucleoporin 205	NP_081789	S*VSGFLHFDTATK	S1165	0.05	0.09
NP	Gata3	trans-acting T-cell-specific transcription factor GATA-3	NP_032117	DVS*PDPSLSTPGSAGSAR	S161	0.05	N/A
NP	Basp1	brain acid soluble protein 1	NP_081671	AEGAGTEEEGT*PK	T36	0.04	0.09†
NE	Tmpo	lamina-associated polypeptide 2 isoform delta	NP_001073599	S*STPLPTVSSSAENTR	S157	0.04	0.03
NP	Myh9	myosin-9 isoform 1	NP_071855	GTGDCS*DEEVDGK	S1943	0.04	0.11
NP	Nop56	nucleolar protein 56	NP_077155	EEVAS*EPEEAASPTTPK	S536	0.04	-0.05
NP	Nup98	nucleoporin 98	NP_075355	YGLQDS*DEEEEEHPPK	S888	0.04	0.07
NP	Plekha6	pleckstrin homology domain-containing family A member 6 isoform 1	NP_891846	T*KSPAEEELTPSAVVR	T899	0.04	0.22†
NE	Pml	protein PML isoform 1	NP_032910	VPAPPGS*PCR	S17	0.04	N/A
NP	Rsf1	remodeling and spacing factor 1	NP_001074736	DIQKLS*PIPEEVVR	S608	0.04	-0.12†
NP	Rbm39	RNA-binding protein 39	NP_573505	DKS*PVREPIDNLTPEER	S136	0.04	0.02
NE	Srrm1	serine/arginine repetitive matrix protein 1 isoform 1	NP_058079	APQTSS*PPPVR	S714	0.04	-0.04
NP	Spna2	spectrin alpha chain, brain isoform 1	NP_001070022	S*LQQLAEER	S1197	0.04	0.05
NP	H2afy	core histone macro-H2A.1 isoform 2	NP_001152985	AASADSTTEGT*PTDGFTVLSTK	T177	0.03	0.05
NE	Dkc1	H/ACA ribonucleoprotein complex subunit 4	NP_001025478	VKVVEEMS*E	S508	0.03	-0.14
NP	Hnrnpc	heterogeneous nuclear ribonucleoproteins C1/C2 isoform 2	NP_001164452	QADLSFSS*PVEMK	S219	0.03	-0.10†
NP	Ilf3	interleukin enhancer-binding factor 3 isoform 1	NP_034691	RPMEEDGEEKS*PSK	S395	0.03	-0.03
NE	Krt8	keratin, type II cytoskeletal 8	NP_112447	S*FTSGPGAR	S24	0.03	0.00
NE	Pphln1	periphilin-1 isoform 1	NP_666174	DAS*PSSSSAVASSK	S219	0.03	N/A
NP	Gm5196	PREDICTED: chromobox protein homolog 3-like	XP_003085921	SLS*DSESDDSK	S95	0.03	-0.03
NE	G3bp1	ras GTPase-activating protein-binding protein 1	NP_038744	STS*PAPADVAPAQEDLR	S231	0.03	-0.02
NE	Rbm15	RNA binding motif protein 15	NP_001039272	SLS*PGGAALGYR	S293	0.03	-0.25
NE	Srrm1	serine/arginine repetitive matrix protein 1 isoform 1	NP_058079	TAS*PPPPPK	S635	0.03	-0.04
NE	Pds5b	sister chromatid cohesion protein PDS5 homolog B	NP_780519	AES*PETSAVESTQSTPQK	S1356	0.03	0.12
NP	Supt5h	transcription elongation factor SPT5	NP_038704	DVTNLTVGGFTPMS*PR	S664	0.03	0.02
NP	Ahnak	AHNAK nucleoprotein isoform 1	NP_033773	GHYEVTGS*DDEAGK	S5607	0.02	0.15†
NE	Gm5803	predicted gene 5803	NP_001159443	SES*PKEPEQLR	S6	0.02	-0.08
NP	Zmynd8	protein kinase C-binding protein 1 isoform 1	NP_081506	SNS*PVSEKPDPTPAK	S678^	0.02	-0.14
NE	Srrm2	serine/arginine repetitive matrix protein 2	NP_780438	VS*SPVLETVQQR	S1263	0.02	0.07
NE	Pds5b	sister chromatid cohesion protein PDS5 homolog B	NP_780519	METVSNASSSSNPSS*PGR	S1166	0.02	0.12
NE	Trip12	thyroid hormone receptor interactor 12	NP_598736	S*ESPPAELPSLR	S310	0.02	0.04
NP	2510012J08Rik	uncharacterized protein C19orf29 homolog	NP_081657	S*PGTATLALSQQQSLQER	S148	0.02	0.12
NE	Ahnak	AHNAK nucleoprotein isoform 1	NP_033773	LPS*GSGPASPTTGSAVDIR	S211	0.01	0.12
NP	Hdgf	hepatoma-derived growth factor	NP_032257	AGDVLEDS*PK	S165	0.01	0.14
NP	Hmg20a	high mobility group protein 20A	NP_080088	S*PLTGYVR	S104^	0.01	-0.06
NE	Nop56	nucleolar protein 56	NP_077155	EEVAS*EPEEAASPTTPK	S536	0.01	-0.16
NP	Psip1	PC4 and SFRS1-interacting protein	NP_598709	ASS*DVEVEEK	S106	0.01	0.09
NE	G3bp1	ras GTPase-activating protein-binding protein 1	NP_038744	ST*SPAPADVAPAQEDLR	T230^	0.01	-0.02
NE	Sltm	SAFB-like transcription modulator isoform b	NP_080613	DVQDAIAQS*PEK	S271	0.01	-0.01
NE	Srrm1	serine/arginine repetitive matrix protein 1 isoform 1	NP_058079	RLS*PSAS*PPR	S387^, S391^	0.01	-0.04
NE	Srrm2	serine/arginine repetitive matrix protein 2	NP_780438	VSS*PVLETVQQR	S1264^	0.01	0.07
NP	Sf3b1	splicing factor 3B subunit 1	NP_112456	TMIIS*PERLDPFADGGK	S129	0.01	-0.10
NP	Zfp148	zinc finger protein 148	NP_035879	GGLLTSEEDSGFSTS*PK	S306	0.01	-0.16†
NE	Zfp608	zinc finger protein 608	NP_786927	APGS*PGAGNPPGTPK	S626	0.01	N/A
NE	Bclaf1	bcl-2-associated transcription factor 1 isoform 2	NP_722482	IDIS*PSALR	S654^	0.00	0.13
NP	Evpl	envoplakin	NP_079552	AAS*PTLPR	S2026^	0.00	0.02
NE	Hnrnpul2	heterogeneous nuclear ribonucleoprotein U-like protein 2	NP_001074665	S*GDETPGSEAPGDK	S159	0.00	-0.02
NP	Lad1	ladinin-1	NP_598425	AQWGSKPSTS*LDAEV	S523	0.00	0.02
NP	Plec	plectin isoform 1g	NP_958795	SSS*VGSSSSYPISSAGPR	S4252	0.00	-0.06
NP	Pum2	pumilio homolog 2 isoform 1	NP_109648	QAS*PTEVVER	S181	0.00	N/A
NE	Evpl	envoplakin	NP_079552	AAS*PTLPR	S2026^	-0.01	-0.02
NP	Foxk2	forkhead box protein K2	NP_001074401	EGS*PAPLEPEPGASQPK	S389	-0.01	N/A
NP	Krt18	keratin, type I cytoskeletal 18	NP_034794	VRPASS*AASVYAGAGGSGSR	S32	-0.01	0.03
NP	Lmo7	LIM domain only 7	NP_963287	EDSVVAETQLASHS*PEEQR	S813	-0.01	0.11
NP	Mta3	metastasis-associated protein MTA3 isoform 1	NP_001164523	HAELSGS*PLK	S517	-0.01	-0.18
NE	Pcm1	pericentriolar material 1 protein	NP_076151	VTNAIS*PESSPGVGR	S65	-0.01	0.72
NP	Pogz	pogo transposable element with ZNF domain isoform 1	NP_766271	SLDAEPSVPSAAKPSS*PEK	S422	-0.01	-0.01
NP	Lmna	prelamin-A/C isoform A	NP_001002011	SVGGS*GGGSFGDNLVTR	S633	-0.01	0.00
NP	Acin1	apoptotic chromatin condensation inducer in the nucleus isoform 2	NP_075679	SQS*PS*PPPLPEDLEK	S389, S391	-0.02	-0.09
NP	Acin1	apoptotic chromatin condensation inducer in the nucleus isoform 2	NP_075679	SQS*PSPPPLPEDLEK	S389	-0.02	-0.09
NP	Dnmt3a	DNA (cytosine-5)-methyltransferase 3A isoform 1	NP_031898	SEPQPEEGS*PAAGQK	S102	-0.02	-0.06
NE	Khsrp	far upstream element-binding protein 2	NP_034743	VQIS*PDSGGLPER	S182	-0.02	-0.02
NP	Nup98	nucleoporin 98	NP_075355	GETVQEICS*PR	S1027	-0.02	0.07
NP	Plec	plectin isoform 1g	NP_958795	S*SSVGSSSSYPISSAGPR	S4250	-0.02	-0.06
NP	LOC674678	PREDICTED: histone H4-like	XP_981474	IS*GLIYEETR	S48	-0.02	0.00
NP	Lmna	prelamin-A/C isoform A	NP_001002011	S*VGGSGGGSFGDNLVTR	S629	-0.02	0.00
NP	Srrm1	serine/arginine repetitive matrix protein 1 isoform 1	NP_058079	APQTSS*PPPVR	S714	-0.02	0.12
NP	Sipa1l1	signal-induced proliferation-associated 1-like protein 1 isoform 1	NP_766167	LIDLES*PTPESQK	S1528	-0.02	N/A
NP	Ssfa2	sperm-specific antigen 2 homolog	NP_542125	S*QSLPTTLLSPVR	S736	-0.02	N/A
NE	Thrap3	thyroid hormone receptor-associated protein 3	NP_666265	ASVSDLS*PR	S243	-0.02	0.00
NP	Ptpn14	tyrosine-protein phosphatase non-receptor type 14	NP_033002	YVSGSS*PDLVTR	S594	-0.02	0.35
NE	Klf3	Krueppel-like factor 3	NP_032479	GS*PPAAGGSPSSLK	S71	-0.03	N/A
NE	Mecp2	methyl-CpG-binding protein 2 isoform 1	NP_001075448	AETSESSGSAPAVPEASAS*PK	S97	-0.03	-0.16
NP	Nucks1	nuclear ubiquitous casein and cyclin-dependent kinases substrate isoform 1	NP_780503	EEDEEAES*PPEKK	S214	-0.03	N/A
NP	Nop56	nucleolar protein 56	NP_077155	EELAS*DLEEMATSSAK	S513	-0.03	-0.05
NP	Ddx21	nucleolar RNA helicase 2	NP_062426	SNSSDAPGEES*SSETEK	S243	-0.03	0.07
NE	Whsc1	probable histone-lysine N-methyltransferase NSD2 isoform 1	NP_001074571	SSS*AENQEGDPGTDK	S408^	-0.03	N/A
NP	Raly	RNA-binding protein Raly short isoform	NP_001132984	LPAPQEDTAS*EAGT*PQGEVQTR	S254, T258	-0.03	-0.07†
NP	Srrm1	serine/arginine repetitive matrix protein 1 isoform 1	NP_058079	HRPSS*PAT*PPPK	S401, T404	-0.03	0.12
NE	Srrm1	serine/arginine repetitive matrix protein 1 isoform 1	NP_058079	HRPSS*PAT*PPPK	S401, T404	-0.03	-0.04
NP	Scaf1	splicing factor, arginine/serine-rich 19	NP_001008422	APS*PAPAVS*PK	S676, S682	-0.03	N/A
NP	Tcf20	transcription factor 20 isoform b	NP_038864	AGSS*PTQGAQNEAPR	S588	-0.03	-0.08
NE	Acin1	apoptotic chromatin condensation inducer in the nucleus isoform 2	NP_075679	SLS*PLSGTTDTK	S479	-0.04	-0.05
NP	Gsk3b	glycogen synthase kinase-3 beta	NP_062801	GEPNVSY*ICSR	Y216	-0.04	0.25
NP	Lad1	ladinin-1	NP_598425	LPS*VEEAEVSKPSPPASK	S62	-0.04	0.02
NP	Fam83h	protein FAM83H	NP_598848	GDS*TEAAAEER	S1041	-0.04	0.08
NP	G3bp1	ras GTPase-activating protein-binding protein 1	NP_038744	S*TSPAPADVAPAQEDLR	S229	-0.04	0.03
NP	G3bp1	ras GTPase-activating protein-binding protein 1	NP_038744	STS*PAPADVAPAQEDLR	S231	-0.04	0.03
NP	Snw1	SNW domain-containing protein 1	NP_079783	GPPS*PPAPVMHS*PSR	S224, S232	-0.04	0.02
NP	Sf3b2	splicing factor 3b, subunit 2	NP_084385	SSLGQS*ASETEEDTVSISK	S290	-0.04	-0.08
NP	Zfp608	zinc finger protein 608	NP_786927	APGS*PGAGNPPGTPK	S626	-0.04	N/A
NP	Ahnak	AHNAK nucleoprotein isoform 1	NP_033773	LPS*GSGPASPTTGSAVDIR	S211	-0.05	0.15†
NP	Farp1	FERMRhoGEF (Arhgef) and pleckstrin domain protein 1	NP_598843	LGAPENSGIST*LER	T24	-0.05	-0.32
NP	Ocln	occludin	NP_032782	YSS*NGNLETPSK	S369	-0.05	0.11
NP	Fam83h	protein FAM83H	NP_598848	KGS*PTQAYPER	S904	-0.05	0.08
NE	Rbm15	RNA binding motif protein 15	NP_001039272	DRT*PPLLYR	T567	-0.05	-0.25
NP	Raly	RNA-binding protein Raly short isoform	NP_001132984	LPAPQEDT*ASEAGT*PQGEVQTR	T252^, T258^	-0.05	-0.07†
NP	Sipa1l3	signal-induced proliferation-associated 1-like protein 3	NP_001074497	EVS*PAPVVAGQNK	S1358	-0.05	-0.22
NP	Pds5b	sister chromatid cohesion protein PDS5 homolog B	NP_780519	APS*PSQPPK	S1381	-0.05	-0.16
NP	Acin1	apoptotic chromatin condensation inducer in the nucleus isoform 1	NP_062513	TAQVPS*PPR	S299	-0.06	-0.02
NP	Gnl3	guanine nucleotide-binding protein-like 3 long isoform	NP_705775	ELS*PEQSTAGKPSDGSSALDR	S505	-0.06	-0.12
NP	Krt20	keratin, type I cytoskeletal 20	NP_075745	S*LSSSSQGPALSMSGSLYR	S11	-0.06	0.01
NP	Tmpo	lamina-associated polypeptide 2 isoform delta	NP_001073599	GPPDFSSDEEREPT*PVLGSGASVGR	T74	-0.06	0.02
NE	Nop56	nucleolar protein 56	NP_077155	EELAS*DLEEMATSSAK	S513	-0.06	-0.16
NP	Nop58	nucleolar protein 58	NP_061356	EEPLS*EEEPCTSTAVPSPEK	S509	-0.06	-0.05
NP	Phf3	PHD finger protein 3	NP_001074549	NTVDIVDKPENS*PQR	S377	-0.06	N/A
NP	Pnn	pinin	NP_032917	SLS*PGKENINSQEVEK	S443	-0.06	-0.09†
NP	Srrm1	serine/arginine repetitive matrix protein 1 isoform 1	NP_058079	EKS*PELPEPSVR	S220	-0.06	0.12
NP	Srrm1	serine/arginine repetitive matrix protein 1 isoform 1	NP_058079	TAS*PPPPPK	S635	-0.06	0.12
NE	Srrm1	serine/arginine repetitive matrix protein 1 isoform 1	NP_058079	RYS*PPIQR	S616^	-0.06	-0.04
NP	Thrap3	thyroid hormone receptor-associated protein 3	NP_666265	S*PPATGSAYGSSQK	S320	-0.06	-0.14
NE	Acin1	apoptotic chromatin condensation inducer in the nucleus isoform 2	NP_075679	SQS*PSPPPLPEDLEK	S389	-0.07	-0.05
NP	Hsp90ab1	heat shock protein HSP 90-beta	NP_032328	IEDVGS*DEEDDSGK	S255	-0.07	-0.02
NP	Hnrnph2	heterogeneous nuclear ribonucleoprotein H2	NP_063921	HTGPNSPDT*ANDGFVR	T107	-0.07	0.02
NP	Nsd1	histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific	NP_032765	AAS*PQEVTPQADEK	S2472	-0.07	N/A
NP	Krt18	keratin, type I cytoskeletal 18	NP_034794	VRPAS*SAASVYAGAGGSGSR	S31^	-0.07	0.03
NP	Mybbp1a	myb-binding protein 1A	NP_058056	SPAPSNPTLS*PSTPAK	S1253	-0.07	-0.14
NP	Pphln1	periphilin-1 isoform 1	NP_666174	AS*PSSSSAVASSK	S219	-0.07	N/A
NP	Raly	RNA-binding protein Raly short isoform	NP_001132984	LPAPQEDTASEAGT*PQGEVQTR	T258	-0.07	-0.07†
NE	Raly	RNA-binding protein Raly short isoform	NP_001132984	GRLS*PVPVPR	S119	-0.07	-0.08
NP	Stub1	STIP1 homology and U box-containing protein 1	NP_062693	LGTGGGGS*PDKSPSAQELK	S20^	-0.07	N/A
NE	Trp53bp1	tumor suppressor p53-binding protein 1	NP_038763	STPFIVPSS*PTEQGGR	S382	-0.07	-0.21
NP	Zc3h18	zinc finger CCCH domain-containing protein 18 isoform a	NP_001025164	AS*DLEEEENATR	S45	-0.07	-0.09
NP	Arl6ip6	ADP-ribosylation factor-like protein 6-interacting protein 6	NP_075365	VGDGS*PVLPDKR	S80	-0.07†	N/A
NE	Arid1a	AT-rich interactive domain-containing protein 1A	NP_001074288	GPS*PSPVGSPASVAQSR	S697	-0.08	-0.14
NP	Nolc1	nucleolar and coiled-body phosphoprotein 1 isoform B	NP_001034440	AAKES*EEEEEEEETEEK	S561	-0.08	-0.07
NE	Plekha6	pleckstrin homology domain-containing family A member 6 isoform 1	NP_891846	T*KSPAEEELTPSAVVR	T899	-0.08	-0.16
NP	D14Abb1e	protein FAM208A isoform 1	NP_001108351	DAQS*PLLEVDAASVK	S836	-0.08	N/A
NP	Fam83h	protein FAM83H	NP_598848	RGS*PTTGLMEQK	S926	-0.08	0.08
NP	Zc3h13	RIKEN cDNA 3110050K21	NP_080359	SLS*PSHLTEDR	S953	-0.08	N/A
NP	Smarcc1	SWI/SNF complex subunit SMARCC1	NP_033237	RKPS*PS*PPPPTATESR	S327, S329	-0.08	-0.15
NP	Tcf20	transcription factor 20 isoform b	NP_038864	SLT*PPPSSTESK	T1699	-0.08	-0.08
NP	Bclaf1	bcl-2-associated transcription factor 1 isoform 2	NP_722482	IDIS*PSALR	S654	-0.09	-0.12†
NP	Ranbp2	E3 SUMO-protein ligase RanBP2	NP_035370	FESPATGILS*PR	S954	-0.09	0.05
NP	Slu7	pre-mRNA-splicing factor SLU7	NP_945174	LVEQANS*PK	S215	-0.09	-0.20
NP	Rbm15	RNA binding motif protein 15	NP_001039272	SLS*PGGAALGYR	S293	-0.09	-0.17†
NP	Sltm	SAFB-like transcription modulator isoform b	NP_080613	DVQDAIAQS*PEK	S271	-0.09	-0.01
NP	Pds5b	sister chromatid cohesion protein PDS5 homolog B	NP_780519	AES*PETSAVESTQSTPQK	S1356	-0.09	-0.16
NP	Spnb2	spectrin beta chain, brain 1 isoform 1	NP_787030	RPPS*PDPNTK	S2102	-0.09	-0.01
NP	Thrap3	thyroid hormone receptor-associated protein 3	NP_666265	ASVSDLS*PR	S243	-0.09	-0.14
NP	Gm5803	predicted gene 5803	NP_001159443	SES*PKEPEQLR	S6	-0.09†	0.01
NP	Pml	protein PML isoform 1	NP_032910	VPAPPGS*PCR	S17	-0.09†	-0.11
NP	Hnrnpul2	heterogeneous nuclear ribonucleoprotein U-like protein 2	NP_001074665	S*GDETPGSEAPGDK	S159	-0.10	-0.06
NP	Fam83h	protein FAM83H	NP_598848	KGS*PTSGFPNR	S915	-0.10	0.08
NP	Son	protein SON truncated isoform	NP_064357	ESAQAVAVALS*PK	S1723	-0.10	-0.02
NP	Rbm14	RNA-binding protein 14	NP_063922	SQGAVANANST*PPPYER	T572	-0.10	-0.05
NP	Safb	scaffold attachment factor B1	NP_001156772	APTAALS*PEPQDSK	S366	-0.10	-0.09
NP	Sipa1l1	signal-induced proliferation-associated 1-like protein 1 isoform 1	NP_766167	TLS*DESIYSSQR	S1564	-0.10	N/A
NP	Smarcc2	SWI/SNF complex subunit SMARCC2 isoform 3	NP_937803	TLTDEVNS*PDSDRR	S283	-0.10	-0.26
NP	2900026A02Rik	uncharacterized protein KIAA1671	NP_766472	RDES*DEEPPR	S205	-0.10	N/A
NP	Taf3	transcription initiation factor TFIID subunit 3	NP_082024	T*PPPAPVPIPVR	T797	-0.10†	N/A
NP	Epn3	epsin-3	NP_082260	GDDS*PVANGAEPAGQR	S257	-0.11	0.93†
NP	Myst2	histone acetyltransferase KAT7 isoform 1	NP_001181932	S*SGSETEQVVDFSDR	S99^	-0.11	N/A
NP	Krt8	keratin, type II cytoskeletal 8	NP_112447	S*FTSGPGAR	S24	-0.11	0.01
NE	Zc3hc1	nuclear-interacting partner of ALK	NP_766323	LCS*SSSSDTSPR	S406	-0.11	0.43
NP	Ahctf1	protein ELYS	NP_080651	TTPLASPSLS*PGR	S1218	-0.11	0.02
NP	Fam83h	protein FAM83H	NP_598848	KGS*PTPAYPER	S871	-0.11	0.08
NP	Fem1b	protein fem-1 homolog B	NP_034323	VLT*LAALLLNR	T19^	-0.11	N/A
NE	Pbrm1	protein polybromo-1	NP_001074720	AAQQQQPSAS*PR	S1468	-0.11	-0.22
NE	Srrm2	serine/arginine repetitive matrix protein 2	NP_780438	S*PVPSAFSDQSR	S2308	-0.11	0.07
NP	Thrap3	thyroid hormone receptor-associated protein 3	NP_666265	IDIS*PSTFR	S679	-0.11	-0.14
NP	Acin1	apoptotic chromatin condensation inducer in the nucleus isoform 2	NP_075679	SLS*PLSGTTDTK	S479	-0.11†	-0.09
NP	Ddx54	ATP-dependent RNA helicase DDX54	NP_082317	IDDRDS*EEEGPSNQR	S774	-0.12	-0.10
NP	Msh6	DNA mismatch repair protein Msh6	NP_034960	SAAVSASS*PEAK	S63	-0.12	-0.04
NP	Hnrnph2	heterogeneous nuclear ribonucleoprotein H2	NP_063921	HTGPNS*PDTANDGFVR	S104	-0.12	0.02
NP	Abcc1	multidrug resistance-associated protein 1	NP_032602	GSS*QLDVNEEVEALIVK	S290	-0.12	N/A
NE	Safb	scaffold attachment factor B1	NP_001156772	APTAALS*PEPQDSK	S366	-0.12	-0.07
NP	Acin1	apoptotic chromatin condensation inducer in the nucleus isoform 2	NP_075679	PS*PPPLPEDLEK	S391	-0.13	-0.09
NP	Baz2a	bromodomain adjacent to zinc finger domain protein 2A	NP_473419	IMEETS*GIEEEEEEENTTAVHGR	S1040	-0.13	0.06
NP	Cdca7l	cell division cycle-associated 7-like protein	NP_666152	GKEDSAS*DAEDESR	S185	-0.13	0.01
NP	Ep400	E1A-binding protein p400 isoform 1	NP_083613	GFDTS*PEHSLDLGISGR	S886	-0.13	-0.06
NE	Syne2	nesprin-2	NP_001005510	TNS*MSFLPVVK	S4096	-0.13	0.04
NP	Numa1	nuclear mitotic apparatus protein 1	NP_598708	TQPDGTSVPGEPAS*PISQR	S1739	-0.13	-0.08
NP	Ncor2	nuclear receptor corepressor 2 isoform 1	NP_035554	EGT*PPPPPPPR	T1349	-0.13	N/A
NP	LOC100046628	PREDICTED: nucleophosmin-like	XP_001476579	AES*EDEDEEDVK	S125	-0.13	-0.02
NP	Rbm15	RNA binding motif protein 15	NP_001039272	S*LSPGGAALGYR	S291	-0.13	-0.17†
NP	Pds5b	sister chromatid cohesion protein PDS5 homolog B	NP_780519	METVSNASSSSNPSS*PGR	S1166	-0.13	-0.16
NE	Snip1	smad nuclear-interacting protein 1	NP_780455	LS*PEPVAHR	S33	-0.13	N/A
NE	Thrap3	thyroid hormone receptor-associated protein 3	NP_666265	RIDIS*PSTFR	S679^	-0.13	0.00
NP	Gatad2a	transcriptional repressor p66 alpha isoform a	NP_663571	RPPS*PDVIVLSDSEQPSS*PR	S96^, S110^	-0.13	-0.51†
NP	Zbtb44	zinc finger and BTB domain-containing protein 44 isoform b	NP_766353	DGSIS*PVSSECSAVER	S161	-0.13	N/A
NP	Ablim1	actin-binding LIM protein 1 isoform 1	NP_848803	TLS*PTPSAEGYQDVR	S475	-0.14	0.14†
NP	Chd3	chromodomain helicase DNA binding protein 3	NP_666131	ELQGDGPPSS*PTNDPTVK	S765	-0.14	1.02
NP	Lrrc16a	leucine-rich repeat-containing protein 16A	NP_081101	S*SGLISELPSEEGR	S971^	-0.14	0.12†
NP	Fip1l1	pre-mRNA 3'-end-processing factor FIP1 isoform 2	NP_077145	DHS*PTPSVFNSDEER	S443	-0.14	-0.02
NP	Srsf9	serine/arginine-rich splicing factor 9	NP_079849	STS*YGYSR	S190	-0.14	-0.07
NE	Smarcc2	SWI/SNF complex subunit SMARCC2 isoform 3	NP_937803	DMDEPS*PVPNVEEVTLPK	S347	-0.14	-0.16
NP	Thrap3	thyroid hormone receptor-associated protein 3	NP_666265	ERS*PALKS*PLQSVVVR	S248^, S253^	-0.14	-0.14
NP	Ythdc1	YTH domain containing 1	NP_808348	GIS*PIVFDR	S309	-0.14	N/A
NP	Zc3h18	zinc finger CCCH domain-containing protein 18 isoform a	NP_001025164	LGVSVS*PSR	S554	-0.14†	-0.09
NP	Rbbp6	E3 ubiquitin-protein ligase RBBP6 isoform 1	NP_035377	VAGSEGSSSTLVDYTSTSSTGGS*PVR	S1278	-0.15	-0.17†
NP	Mylk	myosin light chain kinase, smooth muscle	NP_647461	SSTGSPTS*PINAEK	S1810^	-0.15	0.04
NP	Raly	RNA-binding protein Raly short isoform	NP_001132984	T*ASEAGTPQGEVQTR	T252	-0.15	-0.07†
NP	Smarcc2	SWI/SNF complex subunit SMARCC2 isoform 3	NP_937803	DMDEPS*PVPNVEEVTLPK	S347	-0.15	-0.26
NP	Trip12	thyroid hormone receptor interactor 12	NP_598736	RSES*PPAELPSLR	S312	-0.15	-0.10
NP	Tmpo	lamina-associated polypeptide 2 isoform delta	NP_001073599	S*S*TPLPTVSSSAENTR	S157, S158	-0.15†	0.02
NP	Bclaf1	bcl-2-associated transcription factor 1 isoform 2	NP_722482	AEGEPQEES*PLK	S175	-0.16	-0.12†
NP	Baz2a	bromodomain adjacent to zinc finger domain protein 2A	NP_473419	ELTGSNASTS*PAR	S1172	-0.16	0.06
NP	Top2b	DNA topoisomerase 2-beta	NP_033435	ASGS*ENEGDYNPGR	S1539	-0.16	-0.06
NE	Zc3h13	RIKEN cDNA 3110050K21	NP_080359	SLS*PSHLTEDR	S953	-0.16	-0.17
NP	Srrm1	serine/arginine repetitive matrix protein 1 isoform 1	NP_058079	AAS*PSPQSVR	S756	-0.16	0.12
NP	Smarcc2	SWI/SNF complex subunit SMARCC2 isoform 3	NP_937803	KRS*PSPSPT*PEAK	S302, T308	-0.16	-0.26
NP	Tmpo	lamina-associated polypeptide 2 isoform delta	NP_001073599	SST*PLPTVSSSAENTR	T159	-0.16†	0.02
NP	Sltm	SAFB-like transcription modulator isoform b	NP_080613	S*PGHMVILNQTK	S534	-0.16†	-0.01
NP	Dido1	death-inducer obliterator 1 isoform 2	NP_808520	S*PPEGDTTLFLSR	S1035	-0.17	-0.04
NP	Lrrc16a	leucine-rich repeat-containing protein 16A	NP_081101	RSS*GLISELPSEEGR	S972	-0.17	0.12†
NE	Numa1	nuclear mitotic apparatus protein 1	NP_598708	TQPDGTSVPGEPAS*PISQR	S1739	-0.17	-0.18
NP	Phc3	polyhomeotic-like protein 3 isoform 1	NP_001159426	MDRT*PPPPTLS*PAAVTVGR	T619, S626	-0.17	N/A
NP	Whsc1	probable histone-lysine N-methyltransferase NSD2 isoform 1	NP_001074571	RSSS*AENQEGDPGTDK	S408	-0.17	-0.15
NP	Trip12	thyroid hormone receptor interactor 12	NP_598736	S*ESPPAELPSLR	S310	-0.17	-0.10
NP	Bclaf1	bcl-2-associated transcription factor 1 isoform 2	NP_722482	Y*SPSQNS*PIHHIPSR	Y281^, S287^	-0.17†	-0.12†
NP	Coil	coilin	NP_057915	VTGS*PAEEDEEETK	S174	-0.17†	-0.13
NP	Srrm2	serine/arginine repetitive matrix protein 2	NP_780438	S*PVPSAFSDQSR	S2308	-0.17†	0.13
NE	Brd8	bromodomain-containing protein 8	NP_084423	AT*PPPSPLLSELLK	T264	-0.18	-0.11
NP	Cgnl1	cingulin-like protein 1	NP_080875	SYGSQPNS*PTSEDLAK	S203	-0.18	0.07
NE	Krt20	keratin, type I cytoskeletal 20	NP_075745	S*LSSSSQGPALSMSGSLYR	S11	-0.18	-0.02
NP	Sorbs2	sorbin and SH3 domain-containing protein 2 isoform 2	NP_766340	SFISSSPS*SPSR	S396^	-0.18	0.18
NP	Rprd1b	regulation of nuclear pre-mRNA domain-containing protein 1B	NP_081710	LSMEDSKS*PPPK	S134	-0.18†	-0.07
NP	Rbm39	RNA-binding protein 39	NP_573505	YRS*PYSGPK	S97	-0.18†	0.02
NP	Arid1a	AT-rich interactive domain-containing protein 1A	NP_001074288	GPS*PSPVGSPASVAQSR	S697	-0.19	-0.21
NE	1700081L11Rik	KAT8 regulatory NSL complex subunit 1	NP_001074514	LS*PSTDSSSNLTNVK	S249	-0.19	N/A
NE	Ncor2	nuclear receptor corepressor 2 isoform 1	NP_035554	EGT*PPPPPPPR	T1349	-0.19	N/A
NP	Pkp2	plakophilin-2	NP_080439	TSS*VPEYVYK	S82	-0.19	0.00
NP	Tra2a	transformer-2 protein homolog alpha	NP_932770	AHT*PTPGIYMGR	T200	-0.19	0.10
NE	Ahnak	AHNAK nucleoprotein isoform 1	NP_033773	GHYEVTGS*DDEAGK	S5607	-0.20	0.12
NE	Fnbp4	formin-binding protein 4	NP_061298	ALEEGDGSVSGSS*PR	S486	-0.20	0.01
NP	Tomm70a	mitochondrial import receptor subunit TOM70	NP_613065	AS*PALGSGHHDGSGDSLEMSSLDR	S94	-0.21	0.06
NP	Lmna	prelamin-A/C isoform A	NP_001002011	LS*PSPTSQR	S390^	-0.21	0.00
NP	Trp53bp1	tumor suppressor p53-binding protein 1	NP_038763	SEDRPS*SPQVSVAAVETK	S267^	-0.21	-0.09
NE	Trp53bp1	tumor suppressor p53-binding protein 1	NP_038763	SEDRPSS*PQVSVAAVETK	S268	-0.21	-0.21
NP	Rlf	zinc finger protein Rlf	NP_001074482	S*PTGSLEQNPEQAR	S521	-0.21	N/A
NP	Krt8	keratin, type II cytoskeletal 8	NP_112447	S*LDMDGIIAEVR	S259	-0.21†	0.01
NP	Krt8	keratin, type II cytoskeletal 8	NP_112447	VGSSSS*SFR	S46	-0.22	0.01
NP	Scrib	protein scribble homolog	NP_598850	MQS*PELPAPER	S1485	-0.22	0.13†
NP	Trim28	transcription intermediary factor 1-beta	NP_035718	S*RSGEGEVSGLLR	S471	-0.22	-0.27†
NP	Trp53bp1	tumor suppressor p53-binding protein 1	NP_038763	STPFIVPSS*PTEQGGR	S382	-0.22	-0.09
NP	Hnrnph2	heterogeneous nuclear ribonucleoprotein H2	NP_063921	HT*GPNSPDTANDGFVR	T100	-0.22†	0.02
NP	Tmpo	lamina-associated polypeptide 2 isoform delta	NP_001073599	SS*T*PLPTVSSSAENTR	S158, T159	-0.22†	0.02
NP	Fam83h	protein FAM83H	NP_598848	RGS*PVPPVPER	S948	-0.22†	0.08
NP	1700081L11Rik	KAT8 regulatory NSL complex subunit 1	NP_001074514	LS*PSTDSSSNLTNVK	S249	-0.23	N/A
NP	Krt18	keratin, type I cytoskeletal 18	NP_034794	VRPASSAASVYAGAGGSGS*R	S45	-0.23	0.03
NP	Plekha6	pleckstrin homology domain-containing family A member 6 isoform 1	NP_891846	DPSQTS*PLGTPR	S864	-0.23	0.22†
NP	Sorbs2	sorbin and SH3 domain-containing protein 2 isoform 2	NP_766340	VQSS*PNLLAAGR	S28	-0.23	0.18
NE	Trp53bp1	tumor suppressor p53-binding protein 1	NP_038763	MESLGS*PR	S533	-0.23	-0.21
NE	Krt8	keratin, type II cytoskeletal 8	NP_112447	LVSESSDVVS*K	S489	-0.23†	0.00
NP	Pds5b	sister chromatid cohesion protein PDS5 homolog B	NP_780519	METVSNASSSS*NPSS*PGR	S1162, S1166	-0.24	-0.16
NP	Rif1	telomere-associated protein RIF1	NP_780447	SSDS*VDIEEQEEK	S1572	-0.24†	0.04
NP	Arid1b	AT rich interactive domain 1B (Swi1 like)	NP_001078824	SS*PALAAPDASVDPK	S1757	-0.25	-0.28
NP	Nop56	nucleolar protein 56	NP_077155	EEVASEPEEAAS*PTTPK	S543	-0.25	-0.05
NP	Scaf8	protein SCAF8	NP_598884	ASEPVKEPVQTAQS*PAPVEK	S617	-0.25	-0.10
NP	Mark2	serine/threonine-protein kinase MARK2 isoform 1	NP_031954	SRNS*PLLDR	S483^	-0.25†	N/A
NP	Mdc1	mediator of DNA damage checkpoint protein 1	NP_001010833	VLLAADS*EEEGDFPSGR	S168	-0.26	0.16
NP	Mybbp1a	myb-binding protein 1A	NP_058056	DIPSDTQS*PVSTK	S1164	-0.26	-0.14
NP	Pbrm1	protein polybromo-1	NP_001074720	AAQQQQPSAS*PR	S1468	-0.26	-0.08
NP	Trp53bp1	tumor suppressor p53-binding protein 1	NP_038763	SEDRPSS*PQVSVAAVETK	S268	-0.26	-0.09
NE	Tmpo	lamina-associated polypeptide 2 isoform delta	NP_001073599	SST*PLPTVSSSAENTR	T159	-0.26†	0.03
NP	Kdm4b	lysine-specific demethylase 4B	NP_742144	S*PGEATAGVSTLDEAR	S418	-0.26†	N/A
NE	Tpx2	targeting protein for Xklp2	NP_082385	SSELPLTVPVS*PK	S737	-0.26†	0.21
NP	Smc3	structural maintenance of chromosomes protein 3	NP_031816	GSGS*QSSVPSVDQFTGVGIR	S1083	-0.27	-0.06†
NP	Senp7	sentrin-specific protease 7 isoform 1	NP_079759	RAS*SEIVTEGK	S12^	-0.27†	-0.04
NP	Sorbs2	sorbin and SH3 domain-containing protein 2 isoform 2	NP_766340	SFISSSPSS*PSR	S397	-0.28	0.18
NP	Ctnnd1	catenin delta-1 isoform 1	NP_031641	S*GDLGDMEPLK	S920	-0.28†	0.26†
NP	Ncoa5	nuclear receptor coactivator 5	NP_659141	S*SADSLPGPISR	S377	-0.28†	-0.06
NP	Ncl	nucleolin	NP_035010	NLS*FNITEDELK	S403	-0.28†	-0.13
NP	Tjp3	tight junction protein ZO-3	NP_038797	AIAEPES*PGESR	S343	-0.28†	0.14†
NP	Trim28	transcription intermediary factor 1-beta	NP_035718	S*GEGEVSGLLR	S473	-0.28†	-0.27†
NP	Prpf3	U4/U6 small nuclear ribonucleoprotein Prp3	NP_081817	GDDDEES*DEEAVKK	S619	-0.28†	-0.11†
NE	Sorbs2	sorbin and SH3 domain-containing protein 2 isoform 2	NP_766340	SFISSSPSS*PSR	S397	-0.29	0.03
NP	Mcm2	DNA replication licensing factor MCM2	NP_032590	ISDPLTSS*PGR	S27	-0.30	-0.14
NP	Tcfap4	transcription factor AP-4	NP_112459	FIQELSGSS*PK	S124	-0.30	N/A
NE	Tmpo	lamina-associated polypeptide 2 isoform delta	NP_001073599	SST*PLPTVSSS*AENTR	T159, S167	-0.30†	0.03
NP	Syne2	nesprin-2	NP_001005510	TNS*MSFLPVVK	S4096	-0.30†	0.00
NP	Mll2	histone-lysine N-methyltransferase MLL2	NP_001028448	ALS*PVIPIIPR	S4789	-0.31	N/A
NP	Krt19	keratin, type I cytoskeletal 19	NP_032497	FVTSSSGS*YGGVR	S59	-0.31	-0.01
NP	Son	protein SON truncated isoform	NP_064357	SAAS*PVVISIPER	S1794^	-0.31†	-0.02
NP	Krt8	keratin, type II cytoskeletal 8	NP_112447	VGS*SSSSFR	S43	-0.32†	0.01
NE	Rbm25	RNA-binding protein 25	NP_081625	LGASNS*PGQPNSVK	S672	-0.32†	-0.06
NP	Etl4	sickle tail protein isoform a	NP_835160	SIS*PSPSAILER	S361	-0.32†	0.15†
NE	Zfp219	zinc finger protein 219 isoform 1	NP_081524	ADTS*PTYVR	S688^	-0.32†	-0.22
NP	Rbm25	RNA-binding protein 25	NP_081625	LGASNS*PGQPNSVK	S672	-0.33†	-0.06
NP	Ahnak	AHNAK nucleoprotein isoform 1	NP_033773	LRS*EDGVEGDLGETQSR	S136	-0.34	0.15†
NP	Fnbp4	formin-binding protein 4	NP_061298	ALEEGDGSVSGSS*PR	S486	-0.34	N/A
NP	A830080D01Rik	uncharacterized protein CXorf23 homolog	NP_001028644	VQEESYPQS*PR	S205	-0.34	N/A
NE	Tnks1bp1	182 kDa tankyrase-1-binding protein	NP_001074729	GEGVSQVGPGT*PPAPESPR	T533	-0.35	0.06
NP	Top2b	DNA topoisomerase 2-beta	NP_033435	AS*GSENEGDYNPGR	S1537	-0.35†	-0.06
NP	Pcm1	pericentriolar material 1 protein	NP_076151	SNRPVS*ADGNYRPLAK	S957^	-0.35†	0.15
NP	Poldip3	polymerase delta-interacting protein 3	NP_848742	S*PAAFTSPPIGTVTPALK	S127	-0.35†	-0.20†
NP	Tnks1bp1	182 kDa tankyrase-1-binding protein	NP_001074729	SSGSLS*PGLETEDPLEAR	S1375	-0.36	0.05
NP	Mark2	serine/threonine-protein kinase MARK2 isoform 1	NP_031954	VPAS*PLPGLDR	S453	-0.36	N/A
NP	Hnrnpk	heterogeneous nuclear ribonucleoprotein K	NP_079555	DYDDMS*PR	S284	-0.37†	-0.01
NP	Zc3h13	RIKEN cDNA 3110050K21	NP_080359	AAVVAS*PLLDQQR	S242	-0.37†	N/A
NP	Raly	RNA-binding protein Raly short isoform	NP_001132984	GRLS*PVPVPR	S119	-0.38	-0.07†
NE	Ahnak	AHNAK nucleoprotein isoform 1	NP_033773	LPSGSGPAS*PTTGSAVDIR	S217	-0.38†	0.12
NE	Eif4b	eukaryotic translation initiation factor 4B	NP_663600	SQSS*DTEQPSPTSGGGK	S498	-0.38†	N/A
NP	Tmpo	lamina-associated polypeptide 2 isoform delta	NP_001073599	SST*PLPTVSSS*AENTR	T159, S167	-0.38†	0.02
NE	Trp53bp1	tumor suppressor p53-binding protein 1	NP_038763	SEDRPS*SPQVSVAAVETK	S267	-0.40	-0.21
NP	Tfpt	TCF3 fusion partner homolog	NP_076013	PTS*PAPGEGPSGR	S180	-0.41	N/A
NP	Plec	plectin isoform 1a	NP_958796	TSS*EDNLYLAVLR	S21^	-0.42†	N/A
NP	Ahnak	AHNAK nucleoprotein isoform 1	NP_033773	LPSGSGPAS*PTTGSAVDIR	S217	-0.43†	0.15†
NP	Ints1	integrator complex subunit 1	NP_081024	LSST*PPLSALGR	T110	-0.43†	-0.17†
NP	Krt18	keratin, type I cytoskeletal 18	NP_034794	VRPASSAASVYAGAGGS*GSR	S43	-0.44†	0.03
NP	Zfp185	zinc finger protein 185 isoform a	NP_033575	TTSS*PTQELQSPFLAK	S200	-0.45†	N/A
NP	Spnb2	spectrin beta chain, brain 1 isoform 1	NP_787030	GDQVSQNGLPAEQGS*PR	S2137	-0.46†	-0.01
NP	Pkp4	plakophilin-4 isoform 1	NP_080637	VGS*PLTLTDAQTR	S313	-0.47†	0.05
NP	Sept9	septin-9 isoform a	NP_001106958	S*FEVEEIEPPNSTPPR	S30	-0.47†	0.06
NP	Lima1	LIM domain and actin-binding protein 1 isoform b	NP_075550	TSS*LPESSPSK	S207	-0.49†	0.07
NE	Sept9	septin-9 isoform a	NP_001106958	S*FEVEEIEPPNSTPPR	S30	-0.52†	-0.08
NP	Smarca4	transcription activator BRG1 isoform 2	NP_035547	DSEAGSST*PTTSTR	T1390	-0.53	-0.16
NE	Jun	transcription factor AP-1	NP_034721	LAS*PELER	S73	-0.53†	N/A
NP	Ahnak	AHNAK nucleoprotein isoform 1	NP_033773	LPSGS*GPAS*PTTGSAVDIR	S213, S217	-0.54†	0.15†
NP	Numa1	nuclear mitotic apparatus protein 1	NP_598708	VSSETHQGPGT*PESK	T1982	-0.55	-0.08
NE	Smarca4	transcription activator BRG1 isoform 2	NP_035547	DSEAGSST*PTTSTR	T1390	-0.55	-0.16
NP	Tnks1bp1	182 kDa tankyrase-1-binding protein	NP_001074729	SSGS*LSPGLETEDPLEAR	S1373	-0.56	0.05
NP	Ahnak	AHNAK nucleoprotein isoform 1	NP_033773	GGVTGS*PEASISGSK	S5504	-0.57†	0.15†
NE	Ahnak	AHNAK nucleoprotein isoform 1	NP_033773	GGVTGS*PEASISGSK	S5504	-0.57†	0.12
NP	Tcof1	treacle protein isoform 2	NP_035682	NSS*PAVPAPTPEGVQAVNTTK	S853	-0.71	-0.20
NP	Gprc5c	G-protein coupled receptor family C group 5 member C isoform b precursor	NP_671750	ATANSQVMGS*ANSTLR	S402	-0.73†	0.19†
NP	Tjp1	tight junction protein ZO-1 isoform 2	NP_001157046	IDS*PGLKPASQQVYR	S912	-0.77†	N/A
NP	Mllt4	afadin	NP_034936	S*SPNVANQPPS*PGGK	S1172^, S1182^	-0.83†	0.17
NP	Cobl	protein cordon-bleu	NP_766084	TPGNCEPPHS*PK	S1128	-0.83†	N/A
NE	Ahnak	AHNAK nucleoprotein isoform 1	NP_033773	ASLGSLEGEVEAEASS*PK	S5536	-0.93†	0.12
NP	Tjp1	tight junction protein ZO-1 isoform 1	NP_033412	IDS*PGLKPASQQK	S912	-0.95†	0.09†
NP	Ahnak	AHNAK nucleoprotein isoform 1	NP_033773	ASLGSLEGEVEAEASS*PK	S5536	-1.04†	0.15†
NP	Rbm14	RNA-binding protein 14	NP_063922	QPT*PPFFGR	T206	-1.06	-0.05
NP	1810008A18Rik	protein FAM207A	NP_598759	AVEPALPQS*PAGGAGAK	S38	-1.09†	N/A
NP	Aqp2	aquaporin-2	NP_033829	RQS*VELHS*PQSLPR	S256, S261	-1.13†	N/A
NP	Mylk	myosin light chain kinase, smooth muscle	NP_647461	VPAIGSFS*PGEDR	S364	-1.27†	0.04
NP	Gprc5a	retinoic acid-induced protein 3	NP_852109	AQAPAS*PYNDYEGR	S344	-1.36	0.29†
NE	Mylk	myosin light chain kinase, smooth muscle	NP_647461	VPAIGSFS*PGEDR	S364	-1.36†	-0.03