Transcriptomes of Major Nephron Segments

View transcriptomic databases for the PT, TAL, and IMCD. Locate your protein in the kidney using a BLAST ® search Proximal Tubule (PT) Transcriptome Thick Ascending Limb (TAL) Transcriptome Inner Medullary Collecting Duct (IMCD) Transcriptome Blast your amino acid sequence, against the kidney transcriptome databases. Search results will indicate all databases where your protein is found. RefSeq accession numbers (start with "NP" or "XP") and Swiss-Prot numbers can also be used as search criteria, but amino acid sequence is recommended. Enter amino acid sequence or accession number: How do I find this information?  Click here to manually change settings Max sequences returned: 10 50 100 200 Expect threshold: Word size: 2 3 Matrix: PAM30 PAM70 BLOSUM80 BLOSUM62 BLOSUM45 Gap costs: Existence: 11 Extension: 1 Existence: 9 Extension: 2 Existence: 8 Extension: 2 Existence: 7 Extension: 2 Existence: 12 Extension: 1 Existence: 10 Extension: 1 Compositional adjustments: Composition-based statistics Conditional compositional score matrix adjustment Universal compositional score matrix adjustment

Please cite: Huling JC, Pisitkun T, Song JH, Yu MJ, Hoffert JD, Knepper MA. Gene expression databases for kidney epithelial cells. Am J Physiol Renal Physiol. 2012; 302:F401-7 PMID: 22114206 or full text via American Journal of Physiology. Click here for transcriptomes of 14 rat renal tubule segments, or go to: Lee JW, Chou CL, Knepper MA. Deep Sequencing in Microdissected Renal Tubules Identifies Nephron Segment-Specific Transcriptomes. J Am Soc Nephrol. 2015 PMID: 25817355.

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