Transcriptomes of Major Nephron Segments
View transcriptomic databases for the PT, TAL, and IMCD.
Locate your protein in the kidney using a BLAST
®
search
Proximal Tubule (PT)
Transcriptome
Thick Ascending Limb
(TAL) Transcriptome
Inner Medullary Collecting
Duct (IMCD) Transcriptome
Blast your
amino acid
sequence, against the kidney transcriptome databases. Search results will indicate all databases where your protein is found. RefSeq accession numbers (start with "NP" or "XP") and Swiss-Prot numbers can also be used as search criteria, but amino acid sequence is recommended.
Enter amino acid sequence or accession number:
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Max sequences returned:
10
50
100
200
Expect threshold:
Word size:
2
3
Matrix:
PAM30
PAM70
BLOSUM80
BLOSUM62
BLOSUM45
Gap costs:
Existence: 11 Extension: 1
Existence: 9 Extension: 2
Existence: 8 Extension: 2
Existence: 7 Extension: 2
Existence: 12 Extension: 1
Existence: 10 Extension: 1
Compositional adjustments:
Composition-based statistics
Conditional compositional score matrix adjustment
Universal compositional score matrix adjustment
Please cite: Huling JC, Pisitkun T, Song JH, Yu MJ, Hoffert JD, Knepper MA.
Gene expression databases for kidney epithelial cells.
Am J Physiol Renal Physiol. 2012; 302:F401-7
PMID: 22114206
or
full text via American Journal of Physiology
.
Click
here
for transcriptomes of 14 rat renal tubule segments, or go to: Lee JW, Chou CL, Knepper MA.
Deep Sequencing in Microdissected Renal Tubules Identifies Nephron Segment-Specific Transcriptomes.
J Am Soc Nephrol.
2015 PMID:
25817355
.
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