Specialized Proteomics

Nuclear Proteomics in Collecting Duct

mpkCCD Nucleus Proteome Database (Schenk et al., 2012) Quantitative Nuclear Proteomics in mpkCCD Cells (SILAC): Vasopressin Response (Schenk et al., 2012) mpkCCD Nuclear Phosphoproteome: Effect of Vasopressin (Bolger et al., 2012) Rat Renal Inner Medullary Collecting Duct Nuclei: Effect of Vasopressin (Pickering et al., 2016) Rat Renal Inner Medullary Collecting Duct Cytoplasm (Pickering et al., 2016) Transcription Factors in Rat IMCD Nuclei (Pickering et al., 2016) Virtual Western Blots for Rat IMCD Nuclei (8266 Proteins) (Pickering et al., 2016)

Effects of CRISPR Deletion of Specific Protein Kinases on Protein Abundances

Total and Phospho Proteomics: PKA Double Knockout in mpkCCD (Isobe et al., 2017) Effect of PKA Catalytic Alpha Knockout in mpkCCD on Protein Abundances (Raghuram et al., 2020) Effect of PKA Catalytic Beta Knockout in mpkCCD on Protein Abundances (Raghuram et al., 2020)

Dynamic SILAC Determination of Protein Turnover

Protein Half-Lives in Renal mpkCCD Epithelial Cells: Effect of Vasopressin (Sandoval et al., 2013) Effect of Vasopressin on Protein Translation Rates (Sandoval et al., 2013)

Interactomics

Urea Channel UT-A1 Interactome (Chou et al., 2018) Water Channel AQP2 Interactome (Chou et al., 2018) Beta-Catenin Interactome in IMCD Nucleus (Hwang et al., 2017)

Post-Translational Modifications Other Than Phosphorylation

Renal Inner Medullary Carbamylation Database (Claxton et al., 2013)

Renal Inner Medullary Protein Acetylation Database (Claxton et al., 2013)

Renal Inner Medullary Protein Ubiquitylation Database (Claxton et al., 2013) Rat Renal IMCD Lysine Acetylation (Hyndman et al., 2018)

Proteomics in Water-Balance Disorders

Effect of Lithium Administration on Protein Abundances: Microdissected Rat Cortical Collecting Ducts (Sung et al., 2019) IMCD Proteomics: Hypercalcemia Induced Nephrogenic Diabetes Insipidus (Khositseth et al., 2017) IMCD Proteomics: Hypokalemia Induced Nephrogenic Diabetes Insipidus (Khositseth et al., 2015) IMCD Proteomics: Bilateral Ureeteral Obstruction (Somparn et al., 2020)

Collaborative Specialized Proteomic Data

Rat Proximal Convoluted Tubule Proteome - Acidosis (Curthoys et al., 2012-3) Aldosterone Effects on Mouse Distal Tubule Proteome (Jensen TB et al., 2012)

Return

The Kidney Systems Biology Project website was created by Jaya Parulekar, Cameron Grady, and Mark Knepper. Contact us with questions or comments: knep@helix.nih.gov.

NHLBI | NIH | DHHS | USA.gov